ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ SINH THIẾT TUYẾN TIỀN LIỆT TRÊN BỆNH NHÂN BƯỚU TUYẾN TIỀN LIỆT CÓ PSA CAO TRÊN 4NG/ML

Abstract

Background: Prostate cancer is one of the most common cancers in men, accounting for about 15% of all cancers. Definitive diagnosis needs to be based on many factors such as: digital rectal examination, blood PSA, prostate biopsy results. To diagnose prostate cancer early and understand the correlations between clinical symptoms (digital rectal examination), subclinical symptoms (total PSA, ultrasound) and prostate biopsy results, we conduct this study. Objective: To investigate the clinical and subclinical characteristics of prostate cancer patients with PSA higher than 4ng/ml and the correlation between them in the diagnosis and treatment of prostate cancer. prostate. Materials and methods: This is a cross-sectional, prospective study on 112 prostate cancer patients who were eligible for biopsies from March 2021 to March 2023 at the Hospital of Can Tho University of Medicine and Pharmacy. Results: The mean age was 71.48 ± 9.58 years old, the main cause for admission was difficulty in urination 72.30%. The mean total PSA was 97.77 ± 238.27 ng/ml. Prostate cancer detection rate after biopsy reached 35.7% (40/112). The level of differentiation according to the Gleason scale of high malignancy accounts for 52.5%. There was 1 case of severe rectal bleeding and 1 case of severe hematuria stabilized by aggressive medical treatment and blood transfusion. Conclusions: Prostate biopsy is an accurate method in diagnosing prostate cancer and is a safe procedure that can be widely used in qualified medical facilities.