THYROID HORMONE AND SERUM TSH DISORDERS IN FIRST TRIMESTER OF PREGNANT WOMEN AT CAN THO GYNECOLOGYCAL AND OBSTETRIC HOSPITAL

Thi Minh Nguyet Nguyen1,, Quoc Vi Ngu1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Thyroid function changes quite a bit during pregnancy. Most of these changes are physiological, but sometimes lead to thyroid dysfunction, leaving serious consequences for both mother and fetus if not diagnosed and treated promptly. In particular, in the first 3 months of pregnancy, the fetus cannot produce thyroid hormone on its own, so it is completely dependent on the mother. In Viet Nam and especially in Can Tho, there are not many research data on thyroid dysfunction in pregnancy. Objectives: To determine the prevalence of maternal thyroid disorders during the first trimester of pregnancy and to evaluate the related factors of the pregnant women. Materials and method: Across-sectional study in 323 pregnant women in the first trimester of pregnancy at Can Tho Gynecologycal an Obstetric Hospital from April 2021 to March 2023. Levels of free thyroxine (FT4) and thyroid stimulating hormone (TSH) were measured. Results: The prevalence of maternal thyroid disorders during the first trimester of pregnancy was 17.03%. Related factors of maternal thyroid disorders in the first 3 months of pregnancy were history of miscarriage (p=0.043); personal history of thyroid disorders (p<0.001). Conclusion: Maternal thyroid disorders during the first trimester of pregnancy is common and it is related with history of miscarriage and personal history of thyroid disorders

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References

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