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Date Published: 20/08/2022
Online Published: 20/08/2022
Abstract Views: 661
Views PDF: 317
DOI: https://doi.org/10.58490/ctump.2022i50.138
Issue
No. 50 (2022)
Section
Article
How to Cite
Tran, C. L., Nguyen, M. ng, Phan, V. H., Vo, P. M., Nguyen, T. N. T., Nguyen, H. A. U., & Tran, T. H. N. (2022). THE SPIROMETRY CHARACTERISTICS AND SOME FACTORS ASSOCIATED WITH RE-EXACERBATION OF ACUTE ASTHMATIC CHILDREN AGED 6–15 YEARS OLD AT CAN THO CHILDREN’S HOSPITAL. Cantho Journal of Medicine and Pharmacy, 50, 156-163. https://doi.org/10.58490/ctump.2022i50.138 (Original work published 2022)

THE SPIROMETRY CHARACTERISTICS AND SOME FACTORS ASSOCIATED WITH RE-EXACERBATION OF ACUTE ASTHMATIC CHILDREN AGED 6–15 YEARS OLD AT CAN THO CHILDREN'S HOSPITAL

Cong Ly Tran1,, Minh ng Nguyen1, Viet Hung Phan1, Pham Minh Vo1, Thi Nguyen Thao Nguyen1, Huynh Ai Uyen Nguyen1, Thi Huynh Nhu Tran1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

Background: Asthma is a serious global health issue that affects people of all ages. Objectives: The purpose of this study is to describe the pulmonary function characteristics via spirometry as well as determine some factors associated with asthmatic re-exacerbation. Materials and methods: A cross-sectional descriptive study was performed on patients from 6 to 15 years of age with acute asthma hospitalized at Can Tho Children's Hospital from 1/2021 to 5/2022. Results: A total of 60 asthmatic patients were included in the study. The mean age of asthmatic patients was 8.8±1.9 (years), and the male sex accounted for 68.3%. The average forced expiratory volume in the first second (FEV1) was 68.9±21.1% predicted; forced vital capacity (FVC) was 86.5±20.9% predicted; FEV1/FVC was 69.9±13.0%; forced expiratory flow at 25–75% (FEF25–75) was 44.5±21.1% predicted. When comparing the characteristics of pulmonary ventilation function according to the severity of acute asthma, we found statistically significant differences in FEV1 (p=0,002), FVC (p=0,045), FEV1/FVC (p=0.002) and FEF25-75 (p=0.007) between the groups. We recorded that 13.3% of patients had a re-exacerbation of asthma. Patients with re-exacerbation had significantly lower FEV1, FEV1/FVC, and FEF25-75 than those without. Severe acute asthma (p=0.002), FEV1 (p=0.041), FEV1/FVC (p=0.026), and FEF25-75 (p=0.025) were found to be significantly associated with acute asthma re-exacerbation. Conclusion: In the present study, there were significant differences when comparing these mentioned parameters between the groups following the serverity of acute asthma. This study revealed that severe acute asthma, FEV1, FEV1/FVC, FEF25-75 were significantly associated with asthma re-exacerbation.

Article Details

Keywords

Spirometry, asthma, children

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