THE PREVALENCE AND SOME RELATED FACTORS OF POST‐STROKE DEMENTIA

Van Gan Co1,, Thi Minh Duc Nguyen2
1 Can Tho University of Medicine and Pharmacy
2 Tam Anh General Hospital

Main Article Content

Abstract

Background: Vascular dementia is one of the severe consequences of cerebral stroke, causing disability and reducing the quality of life of patients. Early detection and control of risk factors will reduce the incidence of dementia after stroke and help with rehabilitation. Objectives: To determine the prevalence and some related factors of post‐stroke dementia. Materials and methods: A prospective, cross-sectional descriptive study was conducted on 124 stroke patients ≥18 years old treated at the Neurology Department at Can Tho Central General Hospital from April 2021 to February 2023. All patients in the study underwent clinical examination and were assessed for Mini-Mental State Examination test (MMSE) (at admission and at 3 month after stroke). Poststroke dementia was diagnosed at 3 month after stroke according to the DSM-V criteria. Results: The prevalence of post‐stroke dementia is 37.9%. Post-stroke dementia was significantly associated with factors such as: age, loss of work ability, lower level of secondary school education, smoking, recurrent stroke, cortical strategic lesions, multifocal brain lesions. Conclusion: Post‐stroke dementia accounts for a high prevalence. Factors such as age, loss of work ability, lower level of education, smoking, recurrent stroke, cortical strategic lesions, multifocal brain lesions may be risk factors for post-stroke dementia.

Article Details

References

1 GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021. 20, 795-820, https://doi.org/10.1016/S1474-4422(21)00252-0.
2 Lê Văn Tuấn, Vũ Anh Nhị. Giáo trình thần kinh học. Nhà xuất bản đại học quốc gia Thành phố Hồ Chí Minh. 2020. 173-183.
3 Grysiewicz R., Gorelick P. B. Key Neuroanatomical Structures for Post-Stroke Cognitive Impairment. Current Neurology and Neuroscience Reports. 2012. 12(6), 703-708, https://doi.org/10.1007/s11910-012-0315-2.
4 WHO. Recommendations on stroke prevention, diagnosis and therapy. Report of the WHO task force on stroke and other cerebrovascular disorders. Stroke. 1989. 20, 2545-2537.
5 Lê Nguyễn Nhựt Tín, Vũ Anh Nhị, Phan Văn Ý. Tần suất và yếu tố nguy cơ của sa sút trí tuệ sau đột quỵ. Tạp chí y học Thành phố Hồ Chí Minh. 2008. 12(1), 324-329.
6 Association American Psychiatric. Diagnostic And Statistical Manual Of Mental Disorders, Fifth Edition. 2013. 591-643.
7 Nguyễn Thị Phương Nga, Phạm Thị Mỹ Dung, Trương Thị Trang, Trương Kim Anh. Tỷ lệ và các yếu tố nguy cơ của sa sút trí tuệ sau đột quỵ não. Tạp chí y học Thành phố Hồ Chí Minh. 2013. 17(3), 141-146.
8 8Đa khoa Trung Ương Thái Nguyên. Tạp chí Y Dược lâm sàng. 2017. 12(4), 8-13.
9 Nguyễn Thị Kim Thoa, Trần Công Thắng. Nghiên cứu đặc điểm về tỷ lệ và lâm sàng của suy giảm nhận thức và sa sút trí tuệ sau đột quỵ. Tạp chí y học Thành phố Hồ Chí Minh. 2015. 19(1), 257-263.
10 Tamam B., Taşdemir N., Tamam Y. The Prevalence of Dementia Three Months after Stroke and its Risk Factors. Turkish Journal of Psychiatry. 2008. 19(1), 1-9, https://doi.org/10.1161/01.STR.31.7.1494.
11 Pendlebury S. T. Stroke‐related dementia: Rates, risk factors and implications for future research. Maturitas. 2009. 64(3), 165-171, https://doi.org/10.1016/j.maturitas.2009.09.010.
12 El-Sheik W. M., El-Emam A. I., El-Rahman A. A. E. A., Salim G. M. Predictors of dementia after first ischemic stroke. Dement Neuropsychol. 2021. 15(2), 216-222, https://doi.org/10.1590/1980-57642021dn15-020009.
13 D'Abreu A., Ott B. R. Vascular Dementia: Cerebrovascular mechanisms and Clinical managements. 2005. 234-241.