STUDY ON CLINICAL, PARACLINICAL CHARACTERISTICS, AND TREATMENT RESULTS OF HIGH BLOOD PRESSURE IN CHILDREN FROM 5 TO 16 YEARS OLD AT CAN THO CHILDREN'S HOSPITAL IN 2022-2023

Duc Tri Dang 1,, Thi Vui Cao 2, Anh Tuan Nguyen3, Phuong Trang Nguyen3, Thi Bao Ngoc Nguyen3
1 1. Can Tho University of Medicine and Pharmacy
2 Can Tho University of Medicine and Pharmacy
3 Can Tho Children's Hospital

Main Article Content

Abstract

Background: Hypertension was one of the cardiovascular diseases of great concern in children. The problem of treatment as well as controlling blood pressure according to goals has encountered many difficulties. In the Mekong Delta, so far there have been no studies on the characteristics of hypertension in children. Objectives: To describe the epidemiological, clinical, and paraclinical characteristics and treatment characteristics of hypertension in children at Can


Tho Children's Hospital. Materials and method: Descriptive case series was conducted on 60 hypertensive children from 5 to 16 years old who were treated at Can Tho Children's Hospital from July 2022 to April 2023. Epidemiological, clinical and paraclinical characteristics were collected; the results were analyzed to find the relationship with treatment outcomes. Results: Mean age was 10.8 years ± 3.0 years old. The rate of overweight - obese children was 55%. Urine abnormalities were 43.4%. The rate of dyslipidemia was 26.7%. Systolic hypertension (96.7%), diastolic hypertension was 3.3%. Regarding the cause, the secondary/ primary ratio was 55%/45%. The rate of patients successfully treated was 88.3%. The mean hospital stay was 9.2 ± 3.7 days. There was no relationship between 24-hour proteinuria (p=0.663), anemia (p=1.000), hyperglycemia (p=0.315), dyslipidemia (p=0.370) with treatment results. Family history (p=0.000), salty eating habits (p=0.004) were statistically significantly associated with treatment outcomes. Conclusion: Secondary hypertension and grade II hypertension predominated in children. Most children with high blood pressure were treated with antihypertensive drugs.

Article Details

References

1. Göknar N, Çalışkan S. New guidelines for the diagnosis, evaluation, and treatment of pediatric hypertension. Turk Pediatri Ars, 2020, 55(1), 11-22, Doi:10.14744/TurkPediatriArs.2020.92679.
2. Huỳnh Thị Vũ Quỳnh, Nguyễn Thị Thanh Lan. Đặc điểm Tăng huyết áp trẻ em tại Bệnh viện Nhi Đồng 2. Tạp chí Y học Tp. Hồ Chí Minh, 2009, 13(1), 121-127.
3. Phùng Nguyễn Thế Nguyên. Tăng huyếp áp ở trẻ em. Nhi khoa-chương trình sau đại học tập 4. Đại học Y Dược thành phố Hồ Chí Minh, Khoa Y, Bộ Môn Nhi. 2022. 579-622.
4. Joseph T. Flynn, David C. Kaelber, Carissa M. Baker-Smith. Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents. Pediatrics, 2017, 140(3). Doi: 10.1542/peds. 2017-1904.
5. Trương Thị Lệ Chi. Khảo sát tìm nguyên nhân cao huyết áp ở trẻ em. Luận văn tốt nghiệp bác sĩ nội trú. Đại học Y Dược thành phố Hồ Chí Minh, Khoa Y, Bộ Môn Nhi. 1993.
6. Kaberi Dasgupta, Jennifer O’Loughlin, Shunfu Chen. Emergence of sex differences in prevalence of high systolic blood pressure: analysis of a longitudinal adolescent cohort. Circulation, 2006, 114, 2663-2670. DOI: 10.1161/CIRCULATIONAHA.106.624536.
7. Jung FF, Ingelfinger JR. Hypertension in childhood and adolescence. Pediatr Rev, 1993, 5, 169-179. Doi: 10.1542/pir.14-5-169.
8. Đặng Thị Thùy Hương. Tăng huyết áp do mạch máu thận ở bệnh viện Nhi đồng 1 từ tháng 121998 đến tháng 1-2000. Luận văn tốt nghiệp bác sĩ nội trú. Đại học Y Dược thành phố Hồ Chí Minh, Khoa Y, Bộ Môn Nhi. 2000.
9. Sathanur R. Srinivasan, Leann Myers, Gerald S. Berenron. Changes in metabolic syndrome variables since childhood in prehypertensive and hypertensive subjects: The Bogalusa Heart Study. Hypertension, 2006, 48, 33-39. Doi: 10.1161/01.HYP.0000226410.11198.f4.
10. Zhao W, Mo L, Pang Y. Hypertension in adolescents: The role of obesity and family history. J Clin Hypertens (Greenwich), 2021, 23(12), 2065-2070. Doi: 10.1111/jch.14381.