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Date Published: 15/09/2023
Online Published: 15/09/2023
Abstract Views: 241
Views PDF: 209
DOI: https://doi.org/10.58490/ctump.2023i63.1238
Issue
No. 63 (2023)
Section
Article
How to Cite
Mai, H. T., Nguyen, N. N. T., Nguyen, T. N. M., Do, T. T. H., Luong, H. H., Nguyen, N. T., Nguyen, H. D., Nguyen, P. H. T., & Cao, A. P. (2023). SURVEY ON ANTI-HBS CONCENTRATION AND SOME RELATED FACTORS IN HUMANS AFTER 3 INJECTIONS OF HEPATITIS B VACCINES AT CAN THO CENTER OF DISEASE CONTROL IN 2022-2023. Cantho Journal of Medicine and Pharmacy, 63, 149-156. https://doi.org/10.58490/ctump.2023i63.1238

SURVEY ON ANTI-HBS CONCENTRATION AND SOME RELATED FACTORS IN HUMANS AFTER 3 INJECTIONS OF HEPATITIS B VACCINES AT CAN THO CENTER OF DISEASE CONTROL IN 2022-2023

Hieu Tu Mai1,, Ngoc Nha Thao Nguyen1, Thi Nhu Mai Nguyen2, Thi Thu Hien Do1, Hong Hanh Luong2, Ngoc Thanh Nguyen2, Hong Doan Nguyen2, Phan Hong Tham Nguyen2, Anh Phong Cao2
1 Can Tho University of Medicine and Pharmacy
2 Can Tho Centers for Disease Control and Prevention

Main Article Content

Abstract

Background: Viet Nam is one of the countries with a high rate of hepatitis B infection in Southeast Asia. That is a big problem for the health of our people today. However, hepatitis B is a preventable disease by changing lifestyles, activities and prevention behaviors in the community. However, the most effective measure is the hepatitis B vaccine. Objectives: Surveying the rate and level of antibodies (IgG) generated in human blood and determining some factors related to the immune response after 3 doses of hepatitis B vaccine. Materials and method: A cross-sectional descriptive study with analysis based on 157 people ≥ 6 months of age who was injected 3 doses of hepatitis B vaccine and tested for anti-HBs after completion of the final dose of the hepatitis B vaccine series from September 2022 to Jun 2023. Data processing using Microsoft Excel 2016 software and SPSS 22.0 software, using Chi-square (or Fisher) test with 95% CI. Results: 93.6% of people had anti-HBs ≥ 10mUI/mL, of which 84.7% had anti-HBs ≥ 100mUI/mL and 8.9% had antiHBs from 10-100mUI/mL and 6.4% of people with anti-HBs < 10mUI/mL. Research results also show that there is a statistically significant relationship between immune response ability and age, BMI, drinking habits, Comorbidities diseases (Congenital heart disease, kidney failure, diabetes, obesity, immune system defects, human immunodeficiency virus, tuberculosis. Besides, factors were not found to correlate the immune response with sex factor and  smoking habits. Conclusion: The rate of immune response after 3 doses of hepatitis B vaccine was 93.6%. There is a relationship between age, BMI, drinking habits, Comorbidities diseases (Congenital heart disease, kidney failure, diabetes, obesity, immune system defects, human immunodeficiency virus, tuberculosis) and immune response. factors were not found to correlate the immune response with sex factor and  smoking habits.

Article Details

Keywords

vaccine, hepatitis B, antibody levels, Can Tho Centers for Disease Control and Prevention, immune response

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