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Date Published: 20/08/2022
Online Published: 20/08/2022
Abstract Views: 754
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DOI: https://doi.org/10.58490/ctump.2022i50.115
Issue
No. 50 (2022)
Section
Article
How to Cite
Dương, T. T. V., Trương, T. N. H., Phạm, H. K., Trần, X. Q., & Đỗ, T. T. T. (2022). PERIPHERAL BLOOD EOSINOPHILS AS A BIOMARKER FOR PREDICTING COPD EXACERBATION. Cantho Journal of Medicine and Pharmacy, 50, 1-7. https://doi.org/10.58490/ctump.2022i50.115 (Original work published 2022)

PERIPHERAL BLOOD EOSINOPHILS AS A BIOMARKER FOR PREDICTING COPD EXACERBATION

Thị Thanh Vân Dương1,, Thị Như Hảo Trương1, Hoàng Khánh Phạm1, Xuân Quỳnh Trần1, Thị Thanh Trà Đỗ2
1 Can Tho University of Medicine and Pharmacy
2 Can Tho University of Medicine and Pharmacy Hospital

Main Article Content

Abstract

Background: Chronic obstructive pulmonary disease exacerbations increase mortality and treatment cost, as well as decrease lung function, and impair quality of life. Peripheral blood eosinophils are an important prognostic factor of chronic obstructive pulmonary disease exacerbations. Objectives: To analyse the correlation between blood eosinophils and other factors in the prognosis of chronic obstructive pulmonary disease exacerbations. Materials and methods: A prospective cross-sectional study was conducted on 87 patients with stable chronic obstructive pulmonary disease. Results: The mean age was 67.5±9.49, and males accounted for 98.9%. The mean value of blood eosinophils was 386.49±376.82 cells/μL. There was no difference between groups of blood eosinophils <100, 100-300, and ≥300. Blood eosinophil counted ≥300 cells/μL with the GOLD C/ D was significant in the prognosis of exacerbations in the next 3 months. Conclusion: The peripheral blood eosinophils are not an independent risk factor for the prognosis of chronic obstructive pulmonary disease exacerbation. The peripheral blood eosinophils ≥300cells/μL with GOLD C/D is a significant risk factor for occurring chronic obstructive pulmonary disease exacerbation in the future.

Article Details

Keywords

Blood eosinophils, chronic obstructive pulmonary disease, exacerbation

References

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