TÌNH HÌNH ĐỀ KHÁNG KHÁNG SINH CỦA VI KHUẨN ĐƯỜNG RUỘT SINH ESBL TẠI BỆNH VIỆN ĐA KHOA TRUNG TÂM AN GIANG NĂM 2020-2021

Abstract

 Background: The antibiotic resistance of Extended Spectrum β-Lactamase (ESBL) Producing Enterobacteriaceae is increasing. Accurate assessment of antibiotic resistance rates in these groups of bacteria can helps medical doctors to recommend appropriate indications to their medical conditions, improve the efficiency of treatment, and minimize risks for patients. Objectives: Determination of the prevalence of ESBL-Producing Enterobacteriaceae; 2. Determination of the antibiotic resistance rate of ESBL- Producing Enterobacteriaceae. Materials and methods: A crosssectional study was conducted among 2189 ESBL infected patients treated at An Giang Central General Hospital. Results: Escherichia coli accounted for the highest rate with 64.8%, followed by Klebsiella pneumoniae with 30.2%. Proteus mirabilis and Klebsiella oxytoca accounted for 4.5% and 0.6%, respectively. Escherichia coli had the highest rate of resistance to Ampicillin, accounting for 96.5%, followed by Cefazolin, Ceftriaxone and Ciprofloxacin at 85.3%, 78.3% and 75.2%, respectively. Klebsiella pneumoniae was resistant to Ampicillin the highest rate was 92.4%, followed by Cefazolin, Ciprofloxacin and Ampicillim-Sulbactam which accounted for 60.2%, 57.1% and 56.3%, respectively. Klebsiella oxytoca was resistant to Ampicillin the highest rate was 83.3%, followed by Cefazolin, Trimethoprim-Sulfamethoxazole and Ceftriaxone with 72.7%, 66.7% and 58.3%, respectively. Proteus mirabilis resistance to Trimethoprim-Sulfamethoxazole was highest at 92.0%, followed by Ampicillin, Ciprofloxacin and Tobramycin at 90.8%, 84.0% and 72.9%, respectively. Conclusion: Escherichia coli was the most common pathogenic bacteria. Most of the species of bacteria resisted Ampicillin.