Article Sidebar

PDF
Issue: No. 44 (2021)
Section: Article
Date Published: 25/12/2021
Views 7
Downloads 1
How to Cite
Nguyen, P. H. S., Vo, T. T., Pham, K. A. T., & Tran, T. T. T. (2021). BONE MINERAL DENSITY AND ITS ASSOCIATED FACTORS IN VIETNAMESE WOMEN OVER 40 YEAR OLD AT UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL. Cantho Journal of Medicine and Pharmacy, 44, 226-233. https://tapchi.ctump.edu.vn/index.php/ctump/article/view/1070

BONE MINERAL DENSITY AND ITS ASSOCIATED FACTORS IN VIETNAMESE WOMEN OVER 40 YEAR OLD AT UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL

Phan Hai Sam Nguyen1, , Thi Trang Vo1, Kieu Anh Tho Pham1, Thai Thanh Tam Tran1
1 Can Tho University of Medicine and Pharmacy Hospital

Main Article Content

Abstract

Background: Low measured bone mineral density (BMD) in clinical settings is an indirect indicator of osteoporosis and fracture risk. Objectives: To evaluate the mean BMD at the lumbar spine and femoral neck and the correlation between BMD and some associated factors in women over 40 years. Materials and Methods: A prospective cross-sectional study was conducted. The study group included 168 healthy women aged over 40 years having annual health surveillance at Can Tho University of Medicine and Pharmacy Hospital. BMD was measured at both lumbar spine and femoral neck using dual-energy X-ray absorptiometry (DEXA) from 12/2020 to 9/2021. Results: The results recorded that the mean BMD at the lumbar spine and femoral neck were 0,92±0,2g/cm2 and 0,84±0,15g/cm2, respectively. BMD at the lumbar spine and femoral neck had significant positive correlation with height (r=0,353, p<0,001; r=0,394, p<0,001), weight (r=0,435, p<0,001; r=0,414, p<0,001), BMI (r=0,33, p<0,001; r=0,284, p<0,001) while having significant negative correlation with age (r=-0,609, p<0,00; r=-0,561; p<0,001), time elapsed since menopause-TESM (r=-0,495, p<0,001; r=-0,523; p<0,001), and number of giving birth (r=-0,381, p<0,001; r=0,268, p<0,001). Conclusions: The mean BMD at the lumbar spine and femoral neck which had a significant correlation with age, TESM, number of giving birth, height, weight and BMI were relatively high.

Keywords

Osteoporosis, associated factors, BMD, DEXA, women over 40 years of age

Article Details

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

References

1. Lê Dũng (2012), Khảo sát tình trạng loãng xương ở người cao tuổi tại Thành phố Cần Thơ năm 2011, Luận văn Thạc sỹ y tế công cộng, Trường Đại học Y dược Cần Thơ.
2. Nguyễn Thị Ngọc Lan (2015), Khảo sát yếu tố nguy cơ loãng xương ở phụ nữ Việt Nam từ 50 tuổi trở lên và nam giới từ 60 tuổi trở lên, Tạp chí nghiên cứu y học 97 (5), tr.91-98.
3. Hồ Phạm Thục Lan, Đoàn Công Minh, Phạm Ngọc Khánh và cộng sự (2011), Phát triển tiêu chuẩn tỉ trọng mỡ cơ thể cho chẩn đoán béo phì ở người việt, Thời sự y học 04/2011 (59), tr.3-9.
4. Nguyễn Văn Tuấn, Nguyễn Đình Nguyên (2007), Loãng Xương: Nguyên nhân, chẩn đoán, điều trị và phòng ngừa, Nhà xuất bản y học.
5. AlJohara M AlQuaiz, Ambreen Kazi, Salwa Tayel, et al (2014), Prevalence and factors associated with low bone mineral density in Saudi women: A community based survey, BMC Musculoskelet Disord 15: 5.
6. Compston J, Bowring C, Cooper A, et al (2013): Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK: National Osteoporosis Guideline Group (NOGG) update 2013, Maturitas 75(4), pp.392–396.
7. D. Bliuc, N. D. Nguyen, D. Alarkawi, et al (2015), Accelerated bone loss and increased postfracture mortality in elderly women and men, Osteoporosis International, Vol 26, Issue 4, pp.1331–1339.
8. Heidari B, Hosseini R, Javadian Y, et al (2015), Factors affecting bone mineral density in postmenopausal women, Arch Osteoporos 10, pp.15.
9. J Christopher Gallagher and Sri Harsha Tella (2014), Prevention and treatment of postmenopausal osteoporosis, J Steroid Biochem Mol Biol 142, pp.150-170.
10. Margaret L Gourlay, Catherine A Hammett-Stabler, Jordan B Renner and Janet E Rubin (2014), Associations between Body Composition, Hormonal and Lifestyle Factors, Bone Turnover and BMD, J Bone Metab 21(1), pp.61-68.
11. National Institutes of Health (NIH) (2001), NIH Consensus Development Panel on Osteoporosis, JAMA (285), pp.785-795.
12. Neil Binkley, Robert Adler and John P. Bilezikian (2015), Osteoporosis Diagnosis in Men: The T-score Controversy Revisited, Curr Osteoporos Rep 12(4), pp.403–409.
13. Nyaradzo M. Mgodi, Cliff Kelly, Brenda Gati, et al (2015), Factors associated with bone mineral density in healthy African women, Arch Osteoporos 10, pp.206.
14. Rana EL Bikaia, Muhammad R. Tahira, Johanne Tremblaya, et al (2015), Association of agedependent height and bone mineral density decline with increased arterial stiffness and rate of fractures in hypertensive individuals, Journal of Hypertension 33(4), pp.727-735.
15. Wenjia Gu, Kirsten L. Rennie, Xu Lin, et al (2007), Differences in bone mineral status between urban and rural Chinese men and women, Bone Volume 41, Issue 3, pp.393–399.