RESULTS OF EARLY DECOMPRESSIVE CRANIECTOMY IN THE MANAGEMENT OF LARGE SUPRATENTORIAL HEMISPHERIC INFARCTION

Minh Hoang Chau1, , Van Hai Nguyen2, Vo Ky Pham3
1 Can Tho University of Medicine and Pharmacy
2 Dong Thap General Hospital
3 Kien Giang General Hospital

Main Article Content

Abstract

Background: Large hemispheric infarction typically results from the occlusion of major arteries, such as the internal carotid artery or the middle cerebral artery. Early decompressive craniectomy is associated with a reduction in mortality and an increase in the rate of patients with satisfactory functional status. Objectives: To evaluate the clinical outcomes of early decompressive craniectomy in the management of large supratentoral hemispheric infarction at Can Tho Central General Hospital and S.I.S Can Tho International General Hospital. Materials and methods:  A cross-sectional descriptive study involved 42 patients diagnosed with large supratentorial hemispheric infarction who underwent decompressive hemicraniectomy within 48 hours of stroke onset. Surgical outcomes were evaluated using the modified Rankin Scale (mRS) over a 3-month follow-up period. Results: Among the 42 patients studied, males constituted the majority (61.9%), and patients aged over 60 accounted for a higher proportion (52.4%). Left hemispheric infarction was more prevalent (54.8%). At discharge, the in-hospital mortality rate was 7.1%, and 11 patients (26.2%) achieved a favorable outcome (mRS 0-3). At the 3-month follow-up, the proportion of patients with favorable mRS scores increased to 47.6% (n=20). Conclusions: Early decompressive craniectomy for large supratentorial hemispheric infarction can reduce mortality rates and improve functional recovery outcomes. 

Article Details

References

1. Daou B., Kent A. P., Montano M., Chalouhi N., Starke R. M., et al. Decompressive hemicraniectomy: predictors of functional outcome in patients with ischemic stroke. Journal of neurosurgery. 2016. 124(6), 1773-1779, doi:10.3171/2015.6.JNS15729.
2. Jüttler E., Unterberg A., Woitzik J., Bösel J., Amiri H., et al. Hemicraniectomy in older patients with extensive middle-cerebral-artery stroke. New England Journal of Medicine. 2014. 370(12), 1091-1100, doi:10.1056/NEJMoa1311367.
3. Foerch C., Lang J. M., Krause J., Raabe A., Sitzer M., et al. Functional impairment, disability, and quality of life outcome after decompressive hemicraniectomy in malignant middle cerebral artery infarction. Journal of neurosurgery. 2004. 101(2), 248-254, doi:10.3171/jns.2004.101.2.0248.
4. Holtkamp M., Buchheim K., Unterberg A., Hoffmann O., Schielke E., et al. Hemicraniectomy in elderly patients with space occupying media infarction: improved survival but poor functional outcome. Journal of Neurology, Neurosurgery & Psychiatry. 2001. 70(2), 226-228, doi:10.1136/jnnp.70.2.226.
5. Paliwal P., Kazmi F., Teoh H. L., Yeo L. L., Seet R. C., et al. Early decompressive hemicraniectomy for malignant middle cerebral artery infarction in Asian patients: a singlecenter study. World neurosurgery. 2018. 111, e722-e728, doi:10.1016/j.wneu.2017.12.157.
6. Nguyễn Trọng Hiệp, Trần Trung Kiên, Nguyễn Vũ. Đặc điểm lâm sàng, hình ảnh học và các yếu tố liên quan đến kết quả điều trị bệnh nhân nhồi máu não diện rộng được phẫu thuật mở sọ giảm áp. Tạp chí Y học Việt Nam. 2025. 557(2), 80-85, doi:10.51298/vmj.v557i2.16675.
7. Jüttler E., Schwab S., Schmiedek P., Unterberg A., Hennerici M., et al. Decompressive surgery for the treatment of malignant infarction of the middle cerebral artery (DESTINY) a randomized, controlled trial. Stroke. 2007. 38(9), 2518-2525, doi:10.1161/STROKEAHA.107.485649.
8. Vahedi K., Vicaut E., Mateo J., Kurtz A., Orabi M., et al. Sequential-design, multicenter, randomized, controlled trial of early decompressive craniectomy in malignant middle cerebral artery infarction (DECIMAL Trial). Stroke. 2007. 38(9), 2506-2517, doi:10.1161/STROKEAHA.107.485235.
9. Nguyễn Thành Bắc, Phạm Ngọc Hào, Trần Mạnh Cường, Hoàng Mạnh Linh. Nghiên cứu một số yếu tố tiên lượng trong điều trị phẫu thuật mở sọ giải ép nhồi máu não diện rộng do tắc động mạch não giữa. Tạp chí Y học Việt Nam. 2023. 523(2), 310-314, doi:10.51298/vmj.v523i2.4582.
10. Nguyễn Minh Đức, Nguyễn Huy Ngọc, Đào Việt Phương. Kết quả điều trị mở sọ giảm áp ở người bệnh nhồi máu não diện rộng tại Trung tâm Đột quỵ tỉnh Phú Thọ. Tạp chí Y học Việt Nam. 2026. 560(2), 12-16, doi:10.51298/vmj.v560i2.17818.
11. Abouhashem S., Bafaquh M., Assem A., Taha M. M., ELSherif M., et al. Functional outcome and mortality prediction after decompressive craniectomy in patients with malignant middle cerebral artery infarction. Egyptian Journal of Neurosurgery. 2023. 38(1), 1-9, doi:10.1186/s41984-023-00232-x.