CORRELATION OF TISSUE OXYGEN SATURATION (StO₂) WITH HEMODYNAMIC PARAMETERS AND LACTATE IN CHILDREN WITH SEPTIC SHOCK AT CAN THO CHILDREN’S HOSPITAL, IN 2024-2025
Main Article Content
Abstract
Background: Tissue oxygen saturation (StO₂) is a noninvasive parameter that may support the assessment of tissue perfusion in children with septic shock. Objectives: To describe the clinical characteristics, laboratory findings, and treatment outcomes of pediatric septic shock, and to determine the correlations of StO₂ with mean arterial pressure (MAP), shock index, capillary refill time (CRT), lactate, and base excess (BE) at baseline (T0), 6 hours (T6), and 24 hours (T24). Materials and methods: This longitudinal descriptive study included 37 children with septic shock treated at Can Tho Children’s Hospital from 2024 to 2025. Spearman’s correlation analysis was used to assess the associations between StO₂ and the study variables at each time point. Results: The median age was 22.0 months (IQR, 7.5–64.5), and 73.0% were male. The most common clinical manifestations were fever (97.3%), tachypnea or dyspnea (81.1%), and altered consciousness (78.4%). At T0, the median pH was 7.37 (IQR, 7.26–7.44), BE was −10.80 mmol/L (IQR, −15.05 to −3.25), and lactate was 4.03 mmol/L (IQR, 2.99–6.83). The in-hospital mortality rate was 40.5% (15/37). StO₂ was inversely correlated with shock index at T6 (r = −0.357; p = 0.030) and T24 (r = −0.395; p = 0.019). At T24, StO₂ was moderately inversely correlated with lactate (r = −0.439; p = 0.007). No significant correlations were observed between StO₂ and MAP, CRT, or BE at the assessed time points. Conclusions: Higher StO₂ was associated with a lower shock index at 6 and 24 hours and with lower lactate at 24 hours. StO₂ may serve as a useful noninvasive adjunct for monitoring hemodynamic status and tissue oxygenation in children with septic shock.
Keywords
Septic shock, tissue oxygen saturation, StO₂, lactate, shock index, children
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