NGHIÊN CỨU VỀ MỨC ĐỘ ĐAU VÀ PHƯƠNG PHÁP ĐIỀU TRỊ ĐAU Ở BỆNH NHÂN UNG THƯ TẠI KHOA UNG BƯỚU BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ

Abstract

Background: Malignancy-associated pain causes not only physical suffering but also impacts mental health and quality of life, while potentially compromising treatment outcomes. Assessing current symptom characteristics and analgesic patterns is vital to underscore the necessity for advanced pain care for oncology patients. Objectives: To describe the pain profiles and pharmacological interventions and their associated factors among cancer patients at the Oncology Department, Can Tho University of Medicine and Pharmacy Hospital. Materials and methods: A cross-sectional descriptive study was conducted on 85 cancer patients presenting with pain symptoms and receiving analgesic treatment. Results: Pain severity was mild in 40.0%, moderate in 51.8%, and severe in 8.2% of patients. Nociceptive pain was the most prevalent type (85.9%), alongside mixed (12.9%) and neuropathic pain (1.2%). The incidence of neuropathic or mixed pain was significantly lower in patients with a normal BMI compared to underweight individuals (p = 0.008). Regarding treatment, analgesic monotherapy was utilized in 48.2% of cases. Analgesic combination rates were 42.4% for acetaminophen, 15.3% for neuropathic adjuvants, and 8.2% for NSAIDs. Notably, combination analgesia was employed significantly more often in patients with mild pain than those with moderate-to-severe pain (p < 0.001). Conclusion: Moderate pain was the most prevalent intensity, typically occurring via nociceptive or mixed pathways. The study indicates that patients with a normal BMI status had a lower prevalence of neuropathic or mixed pain mechanisms compared to the underweight group. Clinical focus must shift toward optimizing combination therapies. Early nutritional support to preserve physical status may attenuate multifactorial pain mechanisms.