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Issue: No. 42 (2021)
Section: Article
Date Published: 25/10/2021
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Tran, V. K., Nguyen, M. P., & Phan, V. H. (2021). VALIDATION OF PELOD-2 AND PIM 3 SCORES IN MULTIPLE ORGAN DYSFUNCTION SYNDROME CHILDREN AT CAN THO CHILDREN’S HOSPITAL. Cantho Journal of Medicine and Pharmacy, 42, 225-231. https://tapchi.ctump.edu.vn/index.php/ctump/article/view/1755

VALIDATION OF PELOD-2 AND PIM 3 SCORES IN MULTIPLE ORGAN DYSFUNCTION SYNDROME CHILDREN AT CAN THO CHILDREN'S HOSPITAL

Viet Khai Tran1, , Minh Phuong Nguyen1, Viet Hung Phan1
1 Can Tho University of Medicine and Pharmacy

Main Article Content

Abstract

  Background: Multiple Organ Dysfunction Syndrome (MODS) is common in the Pediatric Intensive Care Unit (PICU), its mortality rate remains high. Objectives: validation of PELOD-2 and PIM 3 score in predicting the mortality of Multiple Organ Dysfunction Syndrome. Materials and methods: This cross-sectional study was conducted on 82 cases with multiple organ dysfunction syndrome admitted to the Pediatric Intensive Care Unit at Can Tho Children’s Hospital from 4/2019 to 5/2021. Results: Multiple Organ Dysfunction Syndrome occured in children less than 12 years of age (90.2%), sex ratio male/female = 2.28/1. Three common organ dysfunction were respiratory, cardiovascular and haematological and the overall mortality in MODS was 62.2%. The area under the ROC curve for the PELOD-2 and PIM 3 scores was 0.890 (95%CI: 0.823 – 0.958) and 0.775 (95%CI: 0.674 – 0.875), respectively. The Hosmer and Lemeshow goodness-of-fit test showed a good calibration in both PELOD-2 and PIM 3 scores (PELOD-2: χ2=3.10, p=0.93; PIM 3: χ2=5.09, p=0.75). Conclusion: The PELOD-2 score was better than PIM 3 in predicting the risk of mortality in children with MODS.

Keywords

Multiple organ dysfunction syndrome, PELOD-2, PIM 3, death

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