STUDY ON CLINICAL, SUBCLINICAL CHARACTERISTICS AND THE RESULTS OF TREATMENT FEMALE INFERTILITY BY IN VITRO FERTILIZATION AT PHUONG CHAU INTERNATIONAL HOSPITAL IN 2019
Main Article Content
Abstract
Background: In vitro fertilization (IVF) is a process that creates embryos outside the body human. Currently, the average success rate is about 40-50 percent. There are many factors affecting the results of treatment. Besides, the tests to evaluate ovarian reserve are still controversial and prognosis, which of pregnancy results have not been tested clearly. Objectives: To descrise clinical, subclinical characteristics and cumulative pregnancy outcome in two frozen embryo transfer cycles. Materials and methods: Women have received IVF treatment at Phuong Chau International Hospital from March, 2019 to March, 2020. Studying design: Cross-sectional description, there are currently 180 clients in IVF treatment process with 2 transfers of frozen embryos. Results: Average age in observed group was 32.21 ± 4.0, AMH value was 4.64 ± 2.78, number of secondary AFC cysts was 15.53 ± 5.67, classified as primary infertility was 65.6% and secondary infertility the number of recovered eggs was 34.4%. The pregnancy rates for the first and second embryo transfer were 43.3% and 63.9%, respectively. The prevalece of the first biochemical pregnancy was 18.3%, the second time was 10.0%; The rate of clinical pregnancy were 23.3% and 51.1%, respectively; The result of two cumulative frozen embryo transfer was 78.2%; clinical pregnancy rate was 63.3%. Conclusion: An ovarian stimulation cycle for IVF, IF we had 2 embryos transfer, the rate of clinical pregnancy was 63.3%.
Keywords
In vitro fertilization, cumulative pregnancy
Article Details

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
2. Vương Thị Ngọc Lan, Võ Minh Tuấn (2015), Giá trị các xét nghiệm AMH, FSH và AFC dự đoán đáp ứng Buồng trứng trong thụ tinh trong ống nghiệm. Luận văn tiến sỹ y học- Đại học Y Dược TP HCM.
3. Lê Viết Nguyên Sa, Cao Ngọc Thành (2013). Đánh giá mối liên quan giữa nồng độ FSH, E2, AMH huyết thanh và chỉ số AFC với đáp ứng kích thích Buồng trứng ở Bệnh nhân thụ tinh trong ống nghiệm, Tạp chí Phụ Sản, số11(4), tr. 20-25.
4. Lê Minh Tâm (2017), Nguy cơ thai ngoài tử cung sau chuyển phôi thụ tinh trong ống nghiệm, Tạp chí Y học sinh sản, ố 43, tr. 45-47.
5. Abdullah, R. K., Liu, N., Zhao, Y., Shuang, Y., Shen, Z., Zeng, H., & Wu, J. (2020). Cumulative live-birth, perinatal and obstetric outcomes for POSEIDON groups after IVF/ICSI cycles: a single-center retrospective study. Scientific RepoRtS, 10(1), pp. 1-13.
6. Asada, Y., Morimoto, Y., Nakaoka, Y., Yamasaki, T., Suehiro, Y., Sugimoto & Irahara, M. (2017), Age‐specific serum anti‐Müllerian hormone concentration in Japanese women and its usefulness as a predictor of the ovarian response, Reproductive medicine and biology, 16(4), pp. 364-373.
7. Fréour, T., Barrière, P., & Masson, D. (2017), Anti-müllerian hormone levels and evolution in women of reproductive age with breast cancer treated with chemotherapy, European journal of cancer, (74), pp. 1-8.
8. Iliodromiti, S., Anderson, R. A., & Nelson, S. M. (2015), Technical and performance characteristics of anti-Müllerian hormone and antral follicle count as biomarkers of ovarian response, Human reproduction update, 21(6), pp. 698-710.
9. Kano, M., Sosulski, A. E., Zhang, L., Saatcioglu, H. D., Wang, D., Nagykery, N., & Pépin, D. (2017), AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy, Proceedings of the National Academy of Sciences, 114(9), pp. 1688-1697.
10. Landersoe, S. K., Forman, J. L., Birch Petersen, K., Larsen, E. C., Nøhr, B., Hvidman, H. W., ... & Nyboe Andersen, A. (2020). Ovarian reserve markers in women using various hormonal contraceptives, The European Journal of Contraception & Reproductive Health Care, 25(1), pp. 65-71.
11. Polyzos, N. P., Drakopoulos, P., Parra, J., Pellicer, A., Santos-Ribeiro, S., Tournaye, H., ... & Garcia-Velasco, J. (2018), Cumulative live birth rates according to the number of oocytes retrieved after the first ovarian stimulation for in vitro fertilization/intracytoplasmic sperm injection: a multicenter multinational analysis including 15,000 women. Fertility and sterility, 110(4), 661-670.
12. Tarín, J. J., Pascual, E., Pérez-Hoyos, S., Gómez, R., García-Pérez, M. A., & Cano, A. (2020), Cumulative probabilities of live birth across multiple complete IVF/ICSI cycles: a call for attention, Journal of Assisted Reproduction and Genetics, 37(1), pp. 141-148.