Thanh bên bài viết
Số lượt xem PDF: 121
A CASE REPORT OF PLATELETS PHAGOCYTOSIS BY PERIPHERAL BLOOD MONOCYTES IN A PATIENT WITH SEPSIS
Nội dung chính của bài viết
Tóm tắt
Background: Monocyte plays a crucial role in phagocytosis. This case report describes a 50-year-old female patient with septicemia who manifested leucocytosis with neutrophilia and severe anemia during her infection course. The peripheral blood examination strikingly showed platelet phagocytosed by the monocytes. Methods: patient’s peripheral blood sample was obtained, spread, and stained with Giemsa solution, then examined under light microscopy. Results: several images of platelet phagocytosis by the monocytes were observed. Conclusions: platelet phagocytosis by monocytes can rarely be observed in peripheral blood in infective and inflammatory states such as sepsis, malignant diseases, and especially hemophagocytic syndrome. To our best knowledge, our finding may be the first time reported in Can Tho.
Chi tiết bài viết
Từ khóa
platelet phagocytosis, hemophagocytic syndrome, hemophagocytic lymphohistiocytosis
Tài liệu tham khảo
2. Antonio Coppola, Sreedhar Rao (1982), Phagocytosis of Monocytes and Platelets in a Neutropenic Infant with Septicemia, Annals of clinical and laboratory science, 12 (6), pp. 471-476.
3. Barbara J. Bain (2015), Blood cells - A practical guide, 5th edition, Wiley Blackwell, pp. 130-134.
4. C. Dale, Laurence Boxer, W. Conrad Liles (2008), The phagocytes: neutrophils and monocytes, Blood, 112 (4), pp. 935-945.
5. A. Criswell, Michael A. Breider, Michael R. Bleavins (2001), EDTA-Dependent Platelet Phagocytosis - A Cytochemical, Ultrastructural, and Functional Characterization, Am J Clin Pathol 2001, 115, pp. 376-384.
6. Kiyofumi Hagiwara, Masakazu Sawanobori et al (2006), Reactive hemophagocytic syndrome in a case of systemic lupus erythematosus that was diagnosed by detection of hemophagocytosing macrophages in peripheral blood smears, Mod Rheumatol (2006), 16, pp. 169-171.
7. Kui Hyun Yoon (2013), A Case of Platelet Satellitism with Platelet Phagocytosis by Neutrophils and Plateletneutrophil Agglutination, Lab Med Online, 3 (4), pp. 259-263.
8. Manujasri Wimalachandra, Lallindra Gooneratne (2019), Platelet phagocytosis by a peripheral blood monocyte in a patient with haemophagocytic lymphohistiocytosis, ASH Image bank, American Society of Hematology, USA.
9. Paul La Rosee, AnnaCarin Horne et al (2019), Recommendations for the management of hemophagocytic lymphohistiocytosis in adults, Blood, 133 (23), pp. 2465-2477.
10. Richard Coico, Geoffrey Sunshine (2015), Immunology - A short course, Wiley Blackwell, pp. 13-16.