TUMOUR-RELATED COMPLICATIONS IN PATIENTS WITH STAGE IV COLORECTAL CANCER TREATED WITH CHEMOTHERAPY WITHOUT PRIMARY TUMOR RESECTION
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Background: Although the typical treatment of patients with stage IV colorectal cancer comprises removal of the primary tumor followed by chemotherapy, some studies suggest that in patients with limited symptoms, the first and only treatment should be chemotherapy. Objectives: To evaluate the complications related to the primary tumor in patients with stage IV colorectal cancer treated with chemotherapy without surgery. Materials and methods: This was a retrospective descriptive study, including 28 patients with stage IV colorectal cancer treated with chemotherapy without primary tumor resection. Results: The average age was 61.4 ± 10.7 years (range 30 - 83) and all of them had the performance status of 0-1. During follow-up, four (14.4%) patients experienced complications. Intestinal obstruction was the most common complication in 3 (10.7%) and there was one case of rectovaginal fistula. Emergency procedures were performed on these patients. The rate of complications was higher in patients with peritoneal metastases than in those without. Conclusions: The incidence of major intestinal complications in colorectal cancer patients with unresected metastases is low. Most patients with stage IV colorectal cancer benefit from chemotherapy rather than surgery.
Từ khóa
Colorectal cancer, chemotherapy, surgery, complications
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