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STUDY ON CLINICAL FEATURES, QUALITY OF LIFE AND RESULTS OF TREATMENT ALOPECIA AREATA WITH INTRALESIONAL BETAMETHASONE AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY
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Abstract
Background: Alopecia areata is an autoimmune disease that leads to sudden hair loss. It can have severe psychological effects and negatively impact quality of life. Objectives: To evaluate the quality of life and effectiveness of treatment with Betamethasone in patients with alopecia areata. Materials and method: A descriptive cross-sectional study on 85 patients diagnosed with alopecia areata, quality of life assessment (DLQI) and treated with intradermal Betamethasone. Results: The mean age was 31.02±11.491 with the mean duration of illness being 12.8±16.356 weeks with mild severity accounting for 94.1%. The group with nail damage had a larger lesion area than the group without nail damage (p<0.001). The dermatology life quality index (DLQI) had a mean score of 10.98±8.092 with symptom-sensory affected the most. The average lesion area after 3 months of treatment decreased by 7.233% (p<0.001). Undesirable effects when treated with Betamethasone were pain, itching, skin redness, and folliculitis were respectively 96.5%; 12.9%; 7.1% and 3.5%. After 1 month of treatment, patients did not develop new lesions, accounting for 98.6% of the group, with the initial level of hair loss <25% higher than the group with new lesions (p=0.002). Conclusions: Intradermal Betamethasone is a successful treatment option for alopecia areata.
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Keywords
alopecia areata, Betamethasone, DLQI
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