THE LATEST UPDATE OF THE TREATMENT OF AXIAL SPONDYLOARTHRITIS AND THE MANAGEMENT OF PATIENTS WITH MUSCULOSKELETAL DISEASES DURING THE COVID-19 PANDEMIC

Thai Hoa Nguyen1, , Hoang Long Ngo1, Thi Hong Nhung Thai1, Thanh Hien Huynh1
1 Can Tho University of medicine and pharmacy

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Abstract

Ankylosing spondylitis is a chronic disease. It is generally characterized by irreversible and structural damage of the sacroiliac and spinal joints, and finally, progressive spinal ankylosis due to new bone formation. Clinical presentations of these patients include chronic back pain, morning stiffness, and loss of spinal mobility. Because ankylosing spondylitis can make patients disabled very early, the treatment is neccessarry. In addition to the conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) such as sulfasalazine, methotrexate, and hydroxychloroquine, some biological disease-modifying antirheumatic drugs (bDMARDs), mainly tumor necrosis factor inhibitors and interleukin-17 inhibitors, play a role in limiting the destruction of joints and improving patients’ quality of life. In this article, we update the latest recommendations of the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR) in the clinical practice and management of patients with ankylosing spondylitis during SARS-COV-2.

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References

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