Cantho Journal of Medicine and Pharmacy
https://tapchi.ctump.edu.vn/index.php/ctump
<p class="p0">04/10/2015 Ministry of Information and Communications allowed Can Tho journal of medicine and pharmacy to operate (102 /GP-BTTTT)</p> <p class="p0"><strong>07/16/2015 Can Tho journal of medicine and pharmacy is internationally recognized:ISSN 2354-1210</strong></p> <p class="p0"><strong>In 2016, The journal has been included in the list of medical science journals by The State Council for professorship which is awarded a work score of 0-0.5 points for a published article.</strong></p> <p class="p0">Can Tho Journal of Medicine and Pharmacy welcome original works that haven’t been submitted or published in other medical journals. Posts must contain content related to one of the journal’s categories.</p>Cantho Journal of Medicine and Pharmacyen-USCantho Journal of Medicine and Pharmacy2354-1210KETAMINE- INDUCED CYSTITIS: A CASE REPORT AND LITERATURE REVIEW
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5001
Background: Ketamine-induced cystitis is an increasingly recognized urological complication among individuals with chronic recreational ketamine abuse. Because its clinical manifestations often overlap with those of recurrent urinary tract infection, interstitial cystitis, or other inflammatory bladder disorders, delayed or incorrect diagnosis is common. Case presentation: We report the case of a 33-year-old man with an 8-year history of intranasal ketamine abuse who presented with severe lower urinary tract symptoms, including urinary frequency, urgency, dysuria, gross hematuria, and suprapubic pain. He had previously received multiple courses of treatment for presumed urinary tract infection without clinical improvement. Urinalysis revealed mild leukocyturia, whereas urine culture was negative. Computed tomography of the urinary tract demonstrated a contracted bladder with diffuse irregular bladder wall thickening without evidence of stones or mass lesions. Cystoscopy showed markedly reduced bladder capacity and diffusely hyperemic, inflamed bladder mucosa with bleeding tendency. Histopathologic examination of bladder biopsy specimens revealed chronic cystitis without evidence of malignancy. Based on the history of prolonged ketamine exposure, characteristic clinical presentation, imaging findings, cystoscopic appearance, and histopathologic results, a diagnosis of ketamine-induced cystitis was established. The patient was treated with strict cessation of ketamine use and symptomatic medical therapy, resulting in marked clinical improvement after 7 days. Conclusion: Ketamine-induced cystitis should be considered in young patients presenting with persistent lower urinary tract symptoms, negative urine culture, and poor response to conventional antimicrobial therapy, particularly when there is a history of ketamine use. Careful history taking, combined with imaging, cystoscopy, and histopathologic evaluation, is critical for accurate diagnosis. Absolute cessation of ketamine remains the cornerstone of management and is essential for long-term clinical outcome.Tho HoangThanh Hai NguyenHong Chien LeVan Bun BuiThi Thu Hien Tran
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510329630110.58490/ctjump.2026i103.5001CASE REPORT: ASEPTIC MENINGITIS - A RARE MANIFESTATION OF SYSTEMIC LUPUS ERYTHEMATOSUS: PATHOGENESIS AND LITERATURE REVIEW
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4997
Background: Aseptic meningitis is an extremely rare neuropsychiatric manifestation of systemic lupus erythematosus, occurring in less than 2.7% of patients across various reports. Due to its non-specific presentation, this manifestation is frequently overlooked or misdiagnosed, leading to a delayed clinical diagnosis. Case presentation: A female patient was admitted to the hospital presenting with a headache. Brain magnetic resonance imaging revealed abnormal meningeal enhancement. Cerebrospinal fluid analysis completely ruled out infectious etiologies (bacterial, viral, and fungal), and systemic imaging modalities found no evidence of metastatic leptomeningeal malignancy. Following a multidisciplinary consultation and subsequent immunological testing, the patient was diagnosed with systemic lupus erythematosus based on the 2019 EULAR/ACR classification criteria. Corticosteroid therapy was promptly initiated, resulting in a rapid resolution of both clinical symptoms and neuroimaging findings. Discussion: This case highlights the pivotal role of advanced neuroimaging in the early detection of meningeal involvement. The systematic and sequential exclusion of infectious and malignant causes is a critical step in guiding clinical suspicion toward an underlying systemic autoimmune disease. Conclusion: A comprehensive understanding of the full clinical spectrum of systemic lupus erythematosus, particularly rare neuropsychiatric presentations such as aseptic meningitis, is vital for ensuring timely immunological screening, early therapeutic intervention, and the optimization of patient outcomes.Nu Tra My TonTien Si BuiManh Cuong DangDuc Tuan TranTien Long NguyenThi Loan Tran
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510330230910.58490/ctjump.2026i103.4997OBESITY AND KIDNEY DISEASES
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4339
Obesity has been increasing worldwide over recent decades. According to the World Health Organization, approximately 650 million adults are living with obesity, accounting for 13% of the global population. In Vietnam, the prevalence of obesity in adults has increased more than six-fold from 1975 to 2015. The rising rate of obesity contributes to the growing burden of diseases, including kidney disease. Increases in average body weight and body mass index (BMI) are associated with a higher incidence of chronic kidney disease (CKD) and end-stage kidney disease (ESKD). Obesity not only accelerates the progression of pre-existing kidney diseases but is also an independent risk factor for kidney injury. Its effects on the kidneys occur through multiple mechanisms, influencing both renal structure and function. These mechanisms include: obesityrelated glomerulopathy, imbalance of adipokines, insulin resistance, lipotoxicity, overactivation of the sympathetic nervous system and the renin–angiotensin–aldosterone system (RAAS), local adipose tissue RAAS activation, alterations in gut microbiota, and chronic inflammation. Clinically, obesity-related renal effects manifest as albuminuria/proteinuria, nephrotic-range proteinuria, CKD progression, ESKD, nephrolithiasis, renal cell carcinoma, and renal steatosis. Therefore, obesity should be recognized and managed as a disease, with timely diagnosis to prevent systemic and renal complications. BMI is a simple and practical indicator for diagnosing obesity in clinical practice; however, its accuracy may be limited in patients with CKD. Interventions targeting obesity have demonstrated improvements in clinical outcomes. Current obesity management strategies include lifestyle modification, pharmacotherapy, and bariatric surgery. Nevertheless, treating obesity in individuals with chronic kidney disease remains a major clinical challenge.Doan Minh Tuan Tran
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510331032110.58490/ctjump.2026i103.4339PHOTON-COUNTING CT: TECHNICAL PRINCIPLES, ADVANTAGES, LIMITATIONS AND CLINICAL APPLICATIONS
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5167
Photon-counting computed tomography (PCCT) represents a paradigm shift in computed tomography imaging by enabling direct detection and energy discrimination of individual X-ray photons, as opposed to energy integration in conventional computed tomography systems. This review provides a comprehensive overview of the technical principles, advantages, limitations, and clinical applications of photon-counting computed tomography in modern radiology. Technically, photon-counting computed tomography employs semiconductor detectors to directly convert photons into electrical signals and categorize them based on predefined energy thresholds, enabling continuous spectral imaging and material-specific characterization, including K-edge imaging. Compared with conventional computed tomography and dual-energy computed tomography, photon-counting computed tomography offers superior spatial resolution, improved dose efficiency, reduced electronic noise, and enhanced material decomposition capabilities. Clinically, photoncounting computed tomography has demonstrated significant advantages across cardiovascular, pulmonary, neurological, musculoskeletal, and oncologic imaging, particularly in plaque characterization, interstitial lung disease assessment, and iodine quantification. Despite its promising performance, challenges such as high system cost, technical limitations, and lack of standardization remain. Future developments are expected to establish photon-counting computed tomography as a cornerstone of precision imaging, particularly with the integration of artificial intelligence and advanced multi-contrast agents.Dong Phong Lam
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510332233410.58490/ctjump.2026i103.5167THE RELATIONSHIP BETWEEN KNOWLEDGE, ATTITUDES, AND PRACTICES REGARDING ARTIFICIAL INTELLIGENCE APPLICATION AMONG NURSING STUDENTS
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5079
Background: In the context of digital health transformation, elucidating the correlation among knowledge, attitude, and practice (KAP) regarding artificial intelligence (AI) application in learning among nursing students is essential for designing effective educational interventions. Objectives: To evaluate the correlation among KAP of AI application in learning among nursing students. Materials and methods: A cross-sectional descriptive study was conducted among 428 nursing students at the University of Medicine and Pharmacy at Ho Chi Minh City, using stratified random sampling by academic year. The data collection instrument was the "Exploring Knowledge, Attitudes, and Practices toward Artificial Intelligence" scale developed by Walid Al-Qerem (2023), translated into Vietnamese, with adequate content validity (S-VI/UA=0.97) and reliability (Cronbach's Alpha ranging from 0.71 to 0.84), comprising four parts: demographics, knowledge, attitude, and practice. Spearman correlation and multivariate regression were used to determine the relationships among KAP components, with statistical significance set at p < 0.05. Results: Spearman analysis indicated statistically significant positive correlations among KAP components (p < 0.05). Knowledge showed weak correlations with both attitude and practice, whereas attitude demonstrated a stronger correlation with practice than knowledge did (r = 0.304; p < 0.001). Conclusions: Attitude was a stronger statistically significant predictor of AI application practice than knowledge among nursing students. Training programs should transcend purely theoretical instruction, focusing instead on shifting perceptions, fostering trust, and building readiness to adapt to technology.Ngoc Ha PhamThi Nhu Quynh NguyenDang Tuong Vy Ho
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-251031710.58490/ctjump.2026i103.5079DIRECT MEDICAL COSTS AND WILLINGNESS TO PAY FOR IMPROVING QUALITY OF LIFE AMONG HOSPITALIZED PATIENTS WITH SPINAL DEGENERATION HAVING HEALTH INSURANCE AT HAU GIANG GENERAL HOSPITAL IN 2025–2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5055
Background: Spondylosis is a common musculoskeletal condition that impairs physical function and quality of life and generates healthcare costs. Assessing direct medical costs and patients’ willingness to pay for health improvement may provide useful evidence for healthcare resource management. Objectives: To determine direct medical costs, willingness to pay for a hypothetical treatment aimed at improving quality of life, and related factors among hospitalized patients with spondylosis covered by health insurance at Hau Giang General Hospital during 2025– 2026. Material andMethods: A cross-sectional analytical study was conducted among 194 hospitalized patients with spondylosis covered by health insurance. Data were collected from medical records, itemized hospital bills, and face-to-face interviews. Multivariable linear regression was used to identify factors associated with willingness to pay. Results: The mean age was 70.95 ± 11.10 years, and women accounted for 66.5% of the study population. The mean direct medical cost per hospitalization was 2,759,135 ± 717,278 VND, of which health insurance covered 2,563,306 ± 693,780 VND, equivalent to 92.9% of the total cost. The mean annual willingness to pay for the hypothetical treatment was 13.36 ± 6.29 million VND. After multivariable adjustment, female sex and having no current spouse were associated with lower willingness to pay, whereas higher monthly income was associated with higher willingness to pay (p < 0.05). Conclusion: Health insurance covers the majority of inpatient treatment costs for patients with spinal degeneration. Willingness to pay is primarily influenced by gender, marital status, and income.Hong Doan HuynhNgoc Nha Thao NguyenThi Tuyet Phung Tran
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510381510.58490/ctjump.2026i103.5055CLINICAL AND PARACLINICAL CHARACTERISTICS OF SEPSIS IN CHILDREN AT CAN THO CHILDREN’S HOSPITAL IN 2024-2025
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4455
Background: Pediatric sepsis is a serious pediatric emergency, causing high mortality and leaving severe sequelae. Therefore, this study was conducted to describe the clinical and subclinical characteristics of sepsis in children, and simultaneously determine some factors related to treatment outcomes, contributing to guiding early diagnostic strategies to reduce the mortality rate in this group of pediatric patients. Objectives: 1. To describe the clinical and laboratory characteristics characteristics of pediatric sepsis;2. To determine the prognostic value for disease severity according to the PIRO score in pediatric sepsis. Materials and methods: A case series report on 62 children diagnosed with sepsis and treated at Can Tho Children's Hospital from November 2024 to June 2025. Results: The study recorded that the most common age group was children < 1 year old, accounting for 56.5%. There were 15 cases of septic shock, accounting for 24.2%. The rate of children with underlying diseases accounted for 45.2%. The cut-off point for predicting severity using the PIRO score was 3.5 points, with sensitivity and specificity of 60% and 93.6%, respectively. Conclusion: Pediatric sepsis remains a severe burden, and the PIRO score plays a significant role in the prognosis of severity.Phuoc Sang NguyenThi Bang Tram PhongChi Nhan LeHuu Tai NguyenPhat Tai NgoPhuoc Nguyen Le
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103162110.58490/ctjump.2026i103.4455ASSOCIATION BETWEEN NEWS2 RISK STRATIFICATION AND EARLY OUTCOMES (INTER-HOSPITAL TRANSFER AND MORTALITY WITHIN 24 HOURS OF ADMISSION) IN THE EMERGENCY DEPARTMENT AT CHAU DOC CITY MEDICAL CENTER
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5113
Background: The NEWS2 score is a standardized tool for early risk stratification based on routine physiological parameters. However, evidence regarding the association between NEWS2based risk stratification and early clinical outcomes among patients admitted to emergency departments at primary healthcare facilities remains limited. Objectives: To evaluate the association between NEWS2 risk categories and early outcomes, including inter-hospital transfer and mortality within 24 hours of admission in patients presenting to the Emergency Department. Materials and methods: An analytical cross-sectional study with longitudinal follow-up was conducted on 412 patients aged ≥18 years who were admitted to the Emergency Department of Chau Doc Medical Center between October 2025 and April 2026. The association between NEWS2 risk categories and early clinical outcomes was evaluated using logistic regression, with Firth's penalized likelihood correction applied when necessary. Results: The median NEWS2 score at admission was 4. Patients in the low-risk group accounted for 63.35%, the medium-risk group for 25%, and the high-risk group for 11.65%. Within 24 hours, the rates of inter-hospital transfer, mortality, and continued in-hospital treatment were 9.5%, 0.5%, and 90.0%, respectively. All deaths occurred in the high-risk group. Compared to the low-risk group, medium- and high-risk patients were 10.1 times (95% CI: 3.6–28.3; p <0.001) and 30 times (95% CI: 10.3–87.4; p <0.001) more likely to be transferred, respectively. For the composite adverse outcome, the odds were 9.4-fold (95% CI: 3.5–25.4; p <0.001) and 30.8-fold (95% CI: 11.1–85.5; p <0.001) higher in the medium- and high-risk groups, respectively. Conclusions: NEWS2 risk stratification is associated with early adverse outcomes within 24 hours. NEWS2 is a simple tool that can support risk stratification in district-level emergency settings.Phan Nguyen Duong Nguyen
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103222810.58490/ctjump.2026i103.5113TREATMENT ADHERENCE ACCORDING TO THE SDSCA SCALE AND ASSOCIATED FACTORS AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS AT BAC LIEU GENERAL HOSPITAL IN 2025
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4444
Background: Maintaining treatment adherence plays a crucial role in the effective management of type 2 diabetes mellitus and in reducing the risk of long-term complications. Currently, patients’ treatment adherence is commonly assessed using the Summary of Diabetes SelfCare Activities (SDSCA) scale developed by Toobert et al., which consists of 17 items. Objectives: To investigate the treatment adherence rate according to the SDSCA scale and its association with selected factors among patients with type 2 diabetes mellitus at Bac Lieu General Hospital in 2025. Materials and Methods: A cross-sectional descriptive study was conducted among 390 outpatients diagnosed with type 2 diabetes mellitus. Data were collected using a structured questionnaire, which included socio-demographic characteristics and information related to treatment adherence. Results: The overall rate of treatment adherence was 35.90%. The highest adherence rates were observed in medication use (88.21%) and nutrition (51.28%), while the lowest rates were found in blood glucose monitoring (22.82%) and physical activity (26.92%). Treatment adherence was significantly associated with age, marital status, educational level, duration of disease, and the number of comorbidities (p<0.05). Conclusion: Treatment adherence among patients with type 2 diabetes mellitus remains limited (3%), particularly in the domains of physical activity (26.92%) and blood glucose monitoring (22.82%). The study identified significant associations between treatment adherence and age, marital status, educational level, duration of disease, and comorbidities. Therefore, strengthening health education, counseling, and appropriate supportive interventions is necessary to improve treatment adherence among patients.Thanh Thuy NgoThi Nha Truc PhamThanh Nam Truong
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103293410.58490/ctjump.2026i103.4444CLINICAL FEATURES AND TREATMENT OUTCOMES OF ENDODONTICALLY TREATED MOLARS RESTORED USING SEMI-DIRECT COMPOSITE ONLAY/OVERLAY TECHNIQUE IN CAN THO 2024 – 2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4604
Background: Restoration of endodontically treated molars remains a clinical challenge due to loss of tooth structure and risk of fracture. Semi-direct composite onlay/overlay restoration is a conservative and cost-effective approach to reinforce cuspal coverage while preserving remaining tooth structure. Objectives: To describe the clinical characteristics and evaluate the restorative outcomes of endodontically treated molars restored with semi-direct composite onlays/overlays. Materials and methods: This prospective, single-arm clinical interventional study with 6-month follow-up period included in 60 endodontically treated molars restored using the semi-direct composite onlay/overlay. Clinical procedures were standardized. Results: Performance across all criteria remained promising and stable, achieving an overall success rate of 98.33%, only 1 failure out of 60 cases after 6 months. Conclusions: Semi-direct composite onlay/overlay demonstrate favorable short-term clinical outcomes, represents an effective conservative treatment and costefficient option for restoring function and esthetics in endodontically treated molars.Ngoc Lan Nhu ChauNguyen Quan PhamViet My Pham
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103354110.58490/ctjump.2026i103.4604DRUG INFORMATION NEEDS AND ASSOCIATED FACTORS AMONG PATIENTS AND HEALTHCARE PROFESSIONALS AT CAN THO GYNECOLOGY OBSTETRICS HOSPITAL IN 2025–2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5267
Background: Accurate and timely drug information is essential for rational and safe medication use, particularly in obstetrics and gynecology, where medication-related decisions may affect the mother, fetus, or newborn. Evidence regarding the information needs of patients and healthcare professionals at Can Tho Gynecology Obstetrics Hospital remains limited, while current services are integrated into routine clinical pharmacy activities. Objectives: To determine drug information needs and associated factors among patients and healthcare professionals at the hospital in 2025–2026. Materials and methods: An analytical cross-sectional study was conducted among 234 patients and 215 healthcare professionals. Needs were assessed using a questionnaire with a 4-point Likert scale; a high level was defined as a total score of at least 75% of the maximum score. Associated factors were examined using multivariable logistic regression and reported as adjusted odds ratios (aORs), 95% confidence intervals (95% CIs), and p values. Results: High drug information needs were identified in 91.9% of patients and 86.0% of healthcare professionals. Contraindications had the highest proportion of “very necessary” ratings among patients (37.2%), whereas indications had the highest proportion among healthcare professionals (74.4%). Overall, 96.6% of patients preferred information from healthcare facilities, 98.7% preferred direct questionand-answer counseling at the dispensing site, and 77.8% were satisfied with the hospital’s current response to their information needs. A separate drug information unit was desired by 90.6% of patients and 94.4% of healthcare professionals. The main purposes of information retrieval among healthcare professionals were updating professional knowledge (85.6%) and direct application in practice (78.6%). Patients receiving self-paid services had higher odds of reporting high information needs than those covered by health insurance (aOR=4.491; 95% CI: 1.525–13.224; p=0.006). No statistically significant associated factor was identified among healthcare professionals (p>0.05). Conclusions: Both groups had a high level of drug information need. The hospital should strengthen drug information services, prioritize direct counseling, and improve access to reliable, evidence-based resources.Thi Hong Yen HuynhYen Hao TranThanh Suol Pham
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103424810.58490/ctjump.2026i103.5267STUDY ON CLINICAL, PARACLINICAL CHARACTERISTICS AND THE VALUE OF MAGNETIC RESONANCE IMAGING IN DIAGNOSING THE INVASIVE STAGE OF BLADDER CANCER
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5093
Background: The Vesical Imaging-Reporting and Data System - VI-RADS score on multiparametric magnetic resonance imaging plays an essential role in bladder cancer staging. Objectives: To describe the clinical characteristics and evaluate the diagnostic value of the VI-RADS score in bladder cancer staging. Materials and methods: A cross-sectional descriptive study was conducted on 90 patients with suspected bladder cancer who underwent multiparametric magnetic resonance imaging. Imaging findings were cross-referenced with histopathological results at Binh Dan Hospital from May 2025 to April 2026. Results: The mean patient age was 65.57 ± 11.45 years, with a male predominance of 88.9%. The most common symptom was hematuria, accounting for 88.8%. Histopathology revealed that solitary tumors comprised 65.2%, and transitional cell carcinoma accounted for 94.4%. The VI-RADS score demonstrated diagnostic value for muscle invasion, yielding an area under the curve - AUC ranging from 0.865 to 0.906; p < 0.001. A cutoff > 3 served as the optimal threshold for definitive diagnosis, with an AUC of 0.906, sensitivity of 87.5%, specificity of 93.7%, and accuracy of 91.6%. A cutoff > 2 achieved absolute screening efficacy, with both sensitivity and negative predictive value reaching 100%. Notably, the apparent diffusion coefficient demonstrated a good independent diagnostic value with an AUC of 0.765; p = 0.001, serving as a 'virtual biopsy' that effectively supports VI-RADS when histopathological specimens lack the muscle layer. Conclusions: The VI-RADS score is highly valuable in diagnosing muscle-invasive bladder cancer, and a cutoff > 2 provides optimal screening efficacy.Phi Van VoVan Lam NguyenChi Phong Nguyen
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103495510.58490/ctjump.2026i103.5093STRESS, ANXIETY, DEPRESSION AND RELATED FACTORS AMONG HEALTHCARE WORKERS IN DONG THAP PROVINCE, 2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4759
Background: Mental health issues such as stress, anxiety, and depression are prevalent among healthcare workers worldwide. According to the WHO, approximately one-third of doctors and nurses in European countries have experienced anxiety or depression. In Vietnam, the rates of stress, anxiety, and depression at 10.2%, 12.9%, and 8.5% in Can Tho City. Objective: To determine the prevalence of stress, anxiety, depression, and related factors among healthcare workers in Dong Thap province. Materials and methods: A cross-sectional descriptive study was conducted in January 2026 among 469 healthcare workers currently working at Dong Thap General Hospital and Sa Dec General Hospital, using a self-administered questionnaire with DASS-21, the score for each area of stress, anxiety, and depression is calculated by summing the scores from the 7 corresponding questions and doubling the sum. Results: The prevalence of stress, anxiety, and depression among healthcare workers was 13.0%, 25.4%, and 18.8%, respectively. Age group, seniority, patient pressure, and support from superiors were statistically significantly associated with all three states of stress, anxiety, and depression. Perceptions of workplace safety were statistically significantly associated with anxiety and depression. Furthermore, male healthcare workers have a statistically significantly higher odds ratio of depression compared to female healthcare workers (OR = 1.75; 95% CI: 1.09-2.80; p < 0.05). Conclusion: Provincial medical facilities with high pressure from work, patients, and specific working environments show associations with stress, anxiety, and depression disorders among medical staff. Support and attention from management contribute to improved mental health among healthcare workers.Thi Ngoc Thu PhamPhu Truong Giang PhamThanh Nam Truong
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103566310.58490/ctjump.2026i103.4759STUDY OF ANATOMICAL VARIATIONS OF HEPATIC VASCULATURE USING CONTRAST-ENHANCED COMPUTED TOMOGRAPHY
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5081
Background: Liver has a complex vascular system with numerous anatomical variations, playing a crucial role in diagnostic imaging, hepatobiliary surgery, and liver transplantation. Contrast-enhanced computed tomography (CECT) is an effective method for evaluating these variations prior to treatment. Objectives: To determine the anatomical characteristics and variations of the hepatic arterial system, portal venous system, and hepatic venous system using CECT. Materials and methods: A cross-sectional descriptive study was conducted among 840 patients aged 18 and older who underwent CECT at the Department of Diagnostic Imaging, Can Tho Central General Hospital, from 2024 to 2026. Results: The common hepatic artery originated from the celiac trunk in 94.9% of cases. According to the Michels classification, the classic hepatic arterial anatomy (Type 1) accounted for the highest proportion at 72.9%, while non-Michels variations accounted for 4.6%. According to the Covey classification, the standard portal vein branching pattern was observed in 87.1% of cases; variations of Types 2, 3, 4, and 5 accounted for 7.6%, 1.4%, 2.6%, and 1.3%, respectively. Regarding the hepatic venous system, a common trunk of the middle and left hepatic veins was recorded in 50.7% of cases, and 33.4% of subjects possessed an accessory right hepatic vein draining directly into the inferior vena cava. Conclusions: Anatomical variations of hepatic vasculature occur with a relatively high frequency. Accurate identification of these variations on CECT is of paramount importance for diagnosis, surgical planning, and interventions, contributing to reducing the risk of complications and improving treatment efficacy.Nguyen Hong Nhung TranThi Giao Ha NguyenRoeland Jan Josef HeijboerLe Hoang Nguyen TrinhThai Huy Nguyen
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103647010.58490/ctjump.2026i103.5081EVALUATION OF TREATMENT OUTCOMES WITH LEVETIRACETAM IN PATIENTS WITH EPILEPSY
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4434
Background: Epilepsy is a common chronic neurological disorder that significantly affects patients’ health and quality of life. Levetiracetam is a newer-generation antiepileptic drug that has demonstrated good seizure control efficacy and a favorable safety profile. However, in Vietnam, data evaluating the therapeutic effectiveness of levetiracetam in adult patients with epilepsy remain limited. Objective: To evaluate the treatment outcomes of levetiracetam in hospitalized patients with epilepsy at Can Tho Central General Hospital. Materials and Methods: A cross-sectional descriptive study was conducted on 65 patients aged ≥16 years diagnosed with epilepsy. Seizure control, recurrence, and adverse effects were assessed during the most recent 3-month treatment period. Results: The study was conducted on 65 patients with epilepsy aged 16 years or older. After 3 months of treatment with levetiracetam, 81.5% of patients achieved good seizure control. The seizure recurrence rate was 27.7%, with no recurrence recorded during the first month. Adverse effects occurred in 40.0% of patients, mainly involving psychiatric–behavioral and neurological manifestations; most were mild, transient, and did not require treatment discontinuation. Conclusion: Levetiracetam demonstrated high efficacy in seizure control and good tolerability among the patients with epilepsy included in this study. It is an effective and safe treatment option for patients with epilepsy.Nguyen Phuong TranNhat Quang MaiThi Hong Cua Trinh
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103717610.58490/ctjump.2026i103.4434PREVALENCE OF HYPERTENSION AND SOME FACTORS ASSOCIATED WITH HYPERTENSION AMONG PEOPLE AGED 18 YEARS AND OBOVE IN PHONG DIEN COMMUNE, CAN THO CITY, IN 2025
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4371
Background: Non-communicable diseases have become a major burden in Vietnam, with cardiovascular diseases accounting for the highest proportion (39.5%). Hypertension (HTN) is a key risk factor for cardiovascular diseases and requires effective community control measures. Objectives:To determine the prevalence of hypertension and identify factors associated with hypertension among adults aged 18 years and older in Phong Dien District, Can Tho City, Vietnam, in 2025. Materials and methods: A descriptive cross-sectional study was conducted with a sample size of 465 adults aged 18 years and olde. Results: The overall prevalence of hypertension was 24.3%, the prevalence increased significantly with age, reaching 57.1% in those over 70 years old, with this group having a 21.77 times higher risk compared to those under 25. Educational level was inversely related to hypertension prevalence, with the highest rate (41.7%), The prevalence of hypertension (HTN) was 31% among alcohol consumers, 36.6% among smokers, and 30% among those with high salt intake. Notably, individuals who did not consume fruit exhibited a higher HTN rate of 38.9% compared to other groups. Similarly, those consuming less than one serving of vegetables per day showed a higher prevalence of 38.5%. Finally, the HTN rate among obese individuals reached 42.4%, which was significantly higher than that of their counterparts. Conclusion: The overall prevalence of hypertension was 24.3%, which increased with age and was associated with low educational attainment, alcohol consumption, smoking, high salt intake, low fruit and vegetable consumption, and obesity. These findings highlight the need to strengthen hypertension prevention and control, particularly among high-risk groups.Van Leo LeVan Thanh Tuan VoPhuong The Bao LeVan Khoa PhamNguyen Hoang An DuongThanh Trieu TruongDang Hong TranHuu Hieu NguyenVan Quang VoVan Loan To
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-25103778310.58490/ctjump.2026i103.4371THE STATUS OF RATIONAL ANTIBIOTIC USE AND ANTIBIOTIC RESISTANCE IN THE TREATMENT OF COMMUNITY-ACQUIRED PNEUMONIA AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN 2025-2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5242
Background: The selection of an appropriate antibiotic regimen plays a pivotal role in the treatment of community-acquired pneumonia. Objectives: To determine antibiotic usage patterns and the rate of rational antibiotic use in the treatment of community-acquired pneumonia, as well as the rate of isolated bacteria (based on medical records) and the overall antibiotic resistance rate of causative pathogens, at Can Tho University of Medicine and Pharmacy Hospital during 2025 - 2026. Materials and methods: A cross-sectional descriptive study was conducted on 194 patient records diagnosed with community-acquired pneumonia at the Department of General Internal Medicine, Can Tho University Medical Center Hospital from 01/01/2025 to 28/02/2026. Results: Among 194 medical records of patients diagnosed with community-acquired pneumonia, regimens combining two antibiotics were the most frequently prescribed initial treatment. Empirical antibiotic regimens aligned with clinical guidelines in 70.1% of instances. The most frequently isolated bacterial strains were Streptococcus pneumoniae (30.9%) and Klebsiella pneumoniae (12.4%). High rates of resistance were observed against beta-lactams (35 - 98%) and fluoroquinolones (70 - 79%). Conclusion: The most effective use of antibiotics in treating community-acquired pneumonia is achieved through close collaboration between doctors and healthcare professionals, along with strict adherence to professional guidelines to optimize antibiotic prescription and and rational antibiotic use.Tran Ai Xuan NguyenThanh Suol PhamHoai An TruongThien Vu NguyenAi Linh TieuTran Ai Dang Nguyen
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2026-09-252026-09-25103849010.58490/ctjump.2026i103.5242A STUDY ON THE CLINICAL AND PARACLINICAL CHARACTERISTICS AND PREGNANCY OUTCOMES IN LABORING WOMEN WITH CATEGORY II FETAL HEART RATE TRACING
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4650
Background: Labor is a physiologically stressful process for the fetus, requiring close monitoring by healthcare professionals to promptly detect potential threats to fetal well-being. Objectives: To describe the clinical and paraclinical characteristics, evaluate pregnancy outcomes, and identify associated factors among women presenting with Category II FHR tracings. Materials and methods: The study included 310 pregnant women with Category II CTG during the first stage of labor at the Department of Obstetrics and Gynecology, Binh Duong General Hospital, from May 2025 to July 2026. Results: The mean age was 27.69 ± 7.35 years. The majority of subjects had no underlying maternal comorbidities (95.8%) and no pregnancy complications (87.8%). Rupture of membranes (ROM) occurred in 59.0% of cases, of which 27.9% presented with abnormal amniotic fluid color. Regarding cardiotocography (CTG) characteristics, variable decelerations were predominant at 92.9%, while a normal baseline fetal heart rate (110–160 bpm) was observed in 74.5% of cases. Regarding pregnancy outcomes, the cesarean delivery rate was 47.1% (with fetal distress as the indication in 31.6% of cases); 87.4% of neonates had a 1-minute Apgar score ≥ 7, and 1.9% required admission to the Neonatal Intensive Care Unit (NICU). Multivariate analysis identified statistically significant risk factors associated with adverse neonatal outcomes, including: maternal underlying comorbidities (OR = 14.17), rupture of membranes (OR = 4.26), pregnancy complications (OR = 2.77), and cesarean delivery (OR = 2.70). Conclusion: Clinical and paraclinical profiles were predominantly characterized by rupture of membranes and variable decelerations on CTG. Multivariate model analysis confirmed maternal underlying comorbidities, rupture of membranes, pregnancy complications, and cesarean delivery as significant factors increasing the risk of adverse neonatal outcomes.Duc Tam LamNguyen Trong Nhan LeThi Ngoc Van TangThi Thu Trang Pham
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2026-09-252026-09-25103919810.58490/ctjump.2026i103.4650STUDY ON CLINICAL, SUB-CLINICAL CHARACTERISTICS, ASSOCIATED FACTORS IN PREGNANT WOMEN WITH GESTATIONAL DIABETES MELLITUS AT NINH THUAN GENERAL HOSPITAL IN 2025 - 2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5074
Background: Approximately 14% of pregnant women worldwide are affected by gestational diabetes mellitus (GDM). GDM is associated with adverse pregnancy outcomes, including preterm birth, primary cesarean section, and preeclampsia. Maternal hyperglycemia before delivery can lead to fetal hyperinsulinemia, increasing the risk of macrosomia, neonatal hypoglycemia, hyperbilirubinemia, and other complications. Objectives: To describe the clinical and paraclinical characteristics and associated factors among pregnant women with gestational diabetes mellitus. Materials and methods: A crosssectional study was conducted on 485 pregnant women attending antenatal care at Ninh Thuan Provincial General Hospital. All participants were screened for GDM using a 75-g oral glucose tolerance test (OGTT) at 24–28 weeks of gestation. Results: The prevalence of gestational diabetes mellitus was 18.6%. The mean maternal age was 32.7 ± 5.65 years. The proportions of women who were overweight before pregnancy and who gained more than 12 kg during pregnancy were 26.7% and 36.8%, respectively. GDM was significantly associated with a history of previous GDM, miscarriage, excessive gestational weight gain, and pre-pregnancy overweight (p < 0.05). Conclusion: The prevalence of gestational diabetes mellitus was high, reaching 18.6%. Therefore, greater attention should be paid to routine screening for early detection and appropriate management.Thi Thu Hang HoQuoc Vi NguManh Khuong Nguyen
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2026-09-252026-09-251039910510.58490/ctjump.2026i103.5074EVALUATION OF TREATMENT OUTCOMES AND THE PROGNOSTIC VALUE OF SERUM PROCALCITONIN, CRP AND D-DIMER LEVELS IN PATIENTS WITH ACUTE PANCREATITIS AT VINH LONG GENERAL HOSPITAL
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5077
Background: Acute pancreatitis (AP) represents a critical medico-surgical emergency featuring rapid onset and intricate disease trajectories that significantly jeopardize patient outcomes. Emerging evidence highlights the prognostic utility of serum Procalcitonin, C-reactive protein (CRP), and D-dimer in forecasting AP progression early. Objectives: To assess clinical outcomes and determine the predictive performance of serum Procalcitonin, CRP, and D-dimer levels in AP patients managed at Vinh Long General Hospital. Materials and methods: A crosssectional analytical study was carried out on 40 AP patients admitted to the Department of Gastroenterology, Vinh Long General Hospital, between September 2025 and January 2026. Results: The mean patient age was 45.2 ± 20.3 years (range: 18–87), with a male predominance of 72.5%. Moderately severe and severe AP cases constituted 70% of the cohort. The average length of stay was 8.2 ± 3.0 days, with zero overall mortality. In predicting severe AP, CRP yielded an AUC of 0.790 (sensitivity 64%, specificity 66%, 95% CI: 0.051–0.870); Procalcitonin demonstrated an AUC of 0.704 (sensitivity 67%, specificity 83%, 95% CI: 0.052–0.880); and D-dimer achieved the highest discriminative power with an AUC of 0.804 (sensitivity 92%, specificity 50%, 95% CI: 0.650–0.950). Conclusion: Serum procalcitonin, CRP and D-dimer levels possess high clinical value in predicting the prognosis of moderately severe and severe acute pancreatitis.Vu Phuong NguyenHuu Nhan KhaThanh Duc LePhuc Nguyen TranTrung Hieu LeLe Quang Thang Doan
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2026-09-252026-09-2510310611210.58490/ctjump.2026i103.5077APPROPRIATE ANTIBIOTIC USE IN INPATIENT TREATMENT AT A HOSPITAL IN CAN THO CITY IN 2025
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5097
Background: Irrational use of antibiotics is a major driver of antimicrobial resistance, leading to reduced treatment effectiveness and increased healthcare costs. Objectives: To assess the characteristics and prevalence of rational antibiotic use among inpatients at a hospital in Can Tho City, Vietnam, in 2025. Materials and methods: A retrospective cross-sectional descriptive study was conducted on 312 medical records of hospitalized patients prescribed antibiotics to determine patterns of antibiotic use and to evaluate the overall appropriateness of antibiotic use based on predefined criteria, including indication, dosage, route of administration, duration of therapy, antibiotic combination and antibiotic switching. Results: The beta-lactam group accounted for the highest proportion of antibiotic use (59.8%). Most patients received antibiotics for ≤ 7 days (60.9%) and were treated with monotherapy (56.1%). The majority of cases did not require modification of the initial regimen (61.9%). Among patients who underwent regimen changes, most were adjusted once (66.4%), primarily due to lack of clinical response to the initial antibiotic therapy. The proportion of patients showing clinical improvement or symptom relief was high (92.6%). The overall rate of appropriate antibiotic use was (72.8%). Conclusions: Antibiotic use in the hospital was generally appropriate; however, further optimization is needed through increased use of microbiological testing and the implementation of antimicrobial stewardship programs.Ai Linh TieuThien Vu NguyenHuu Hieu DoGia Hao HoTran Ai Xuan NguyenPhuong Mai MaiThanh Suol Pham
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2026-09-252026-09-2510311312010.58490/ctjump.2026i103.5097RESEARCH MENTORING FOR JUNIOR NURSING FACULTY: A CASE STUDY AT PHAM NGOC THACH UNIVERSITY OF MEDICINE
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4450
Background: Research mentoring contributes to the academic development of junior nursing faculty. Objectives: To describe the mentoring process for a junior faculty member at Pham Ngoc Thach University of Medicine, changes in academic capacity, outcomes, and lessons learned. Materials and methods: A descriptive case study examined the mentoring process from 2020 to 2026 between an experienced mentor and a junior nursing faculty member. Data comprised mentoring journals, academic activities, and mentee feedback. Results: The mentee improved research skills and autonomy; led or participated in four research projects, published eight articles, and supervised two undergraduate theses; received an award at the 2024 National Young Health Science Conference, a Certificate of Merit from the Vietnam Nurses Association, and the title of Outstanding Nurse of Vietnam in 2025. Flexible mentoring, a supportive environment, and the mentee’s proactiveness contributed to these outcomes. Conclusion: Mentoring that combines formal and informal approaches with sustained mentor support may contribute to the academic and professional development of junior faculty.Thi Ha DoThi My Trinh Phan
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2026-09-252026-09-2510312112710.58490/ctjump.2026i103.4450CURRENT STATUS AND CHALLENGES OF ACUPUNCTURE CLINICAL COMPETENCE AMONG VIETNAMESE TRADITIONAL MEDICINE STUDENTS: A QUALITATIVE STUDY USING GROUNDED THEORY
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5042
Background: Acupuncture is an essential non-pharmacological therapy in Vietnamese Traditional Medicine, yet graduates' acupuncture clinical competence and training-system challenges have not been systematically examined. Objectives: To describe the current status of acupuncture clinical competence among newly graduated Vietnamese Traditional Medicine students and to analyze the existing training-system problems affecting this competence. Materials and methods: A qualitative Grounded Theory study combined with the Problem-Centered Interview (PCI) method was conducted on 38 participants (experts, clinicians, lecturers and recent graduates) across 7 provinces/cities in three regions of Vietnam, 2024–2025. Data were coded in three levels using Atlas.ti with consensus between two coders. Results: Thirty-eight interviewees yielded 432 valid data units. Regarding competence, three categories were identified: 1. Lack of ability to evaluate acupuncture outcomes and self-competence; 2. Overall limitations in diagnosis, treatment and clinical management; 3. Limitations in acupoint localization, needling techniques and point combination. Regarding training, three categories emerged: 1. Insufficient personal professional development competence; 2. Limited clinical training resources and curriculum; 3. Lack of theory– practice coherence and consensus. Conclusion: Vietnamese Traditional Medicine graduates demonstrate notable limitations in acupuncture clinical competence, particularly in diagnosis, syndrome differentiation, needling techniques and self-assessment. The foremost priority is a standardized acupuncture competency assessment toolkit – a prerequisite for the competency standards of Decision 3159/QĐ-BYT to become effective.Duy Duc PhamYi GuoHong Hieu Hua
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2026-09-252026-09-2510312813410.58490/ctjump.2026i103.5042CLINICAL CHARACTERISTICS AND TREATMENT OUTCOMES OF CHRONIC URTICARIA WITH BILASTINE 20 MG AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY IN 2025 – 2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4998
Background: Chronic urticaria is a common inflammatory skin disease characterized by recurrent wheals and pruritus, leading to impaired quality of life. Bilastine 20 mg, a second-generation non-sedating H1-antihistamine, is recommended for its management. Objectives: To describe clinical characteristics and evaluate treatment outcomes of chronic urticaria with bilastine 20 mg. Materials and methods: A cross-sectional study was conducted on 50 outpatients with chronic spontaneous urticaria treated with bilastine 20 mg once daily at Can Tho City Dermatology Hospital from 2025 to 2026. Results: Pruritus and wheals were present in all patients. 54,0% patients had no identifiable triggering factors. Mean UAS7 significantly decreased from 5.52 ± 1.15 at baseline to 2.05 ± 0.85 at week 2 and 0.65 ± 0.70 at week 4 (p < 0.001). After 4 weeks, all patients achieved mild disease or complete symptom control. DLQI improved markedly from 13.2 ± 3.4 to 0.9 ± 0.8, with 88% reporting no or minimal quality-of-life impairment. Adverse events were infrequent (6%) and mild. Conclusions: Bilastine 20 mg once daily is an effective and well-tolerated treatment for chronic urticaria, providing significant symptom control and quality-of-life improvement.Minh Huy ThachLe Bang NguyenTran Anh Tuan NguyenThi Le Quyen Nguyen
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510313514110.58490/ctjump.2026i103.4998CLINICAL CHARACTERISTICS AND CLASSIFICATION OF ATROPHIC SCARS AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY IN 2025-2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5010
Background: Atrophic scars are a common dermatologic condition. Although they rarely result in serious medical complications, their predominant facial distribution can lead to substantial aesthetic concerns and adverse psychological impacts. Objectives: To describe the clinical characteristics and classification of atrophic scars at Can Tho Hospital of Dermato-Venereology from 2025 to 2026. Materials and methods: A cross-sectional descriptive study was conducted on 56 patients with atrophic scars at Can Tho Hospital of Dermato-Venereology from April 2025 to February 2026. Results: The mean age of participants was 26.45 ± 7.15 years, with the 21-30-year age group accounting for the largest proportion (55.4%). Female patients predominated (58.9%). The mean age at scar onset was 18.54 ± 3.58 years. Acne vulgaris was the most common etiologic factor (83.9%). The cheeks were the most frequently affected anatomical site (45/56 patients). Boxcar scars were the predominant morphological subtype (87.5%), while mixed scar patterns were observed in 48.2% of patients. According to the qualitative Goodman and Baron scale, most patients had grade 4 atrophic scars (46.4%). More than 20 scars were present in 64.3% of patients. Age ≥30 years and scars caused by varicella or trauma were significantly associated with grade 4 atrophic scars (p = 0.024 and p = 0.008, respectively). Conclusions: Atrophic scars were predominantly secondary to acne vulgaris and therefore occurred mainly in adolescents and young adults, boxcar scars represented the most common morphological subtype, and the cheeks were the most frequently involved anatomical site. Patients aged ≥ 30 years and those with atrophic scars secondary to varicella or trauma were more likely to have grade 4 scars than younger patients and those with acne-related atrophic scars.Mac Thanh Thanh NguyenVan Ba HuynhVan Ha PhamLe Bang Nguyen
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510314214810.58490/ctjump.2026i103.5010EVALUATION OF OUTCOMES OF MICROSURGICAL REPAIR FOR MEDIAN NERVE TRANSECTION AT THE DISTAL ONE-THIRD OF THE FOREARM AND WRIST IN CAN THO, 2025-2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4973
Background: Median nerve laceration at the distal third of the forearm and wrist represents a common peripheral nerve injury of the upper extremity, resulting in impaired fine motor function, diminished grip strength, and sensory disturbance over the palmar surface of the hand. Without timely intervention, patients are at risk of thenar muscle atrophy and permanent functional deficit of the hand. Microsurgical repair is currently regarded as the gold standard treatment; however, studies addressing this condition in the Mekong Delta region remain limited. Objectives: To describe the clinical characteristics and evaluate the functional outcomes of microsurgical median nerve repair in patients presenting with median nerve transection at the distal forearm and wrist. Materials and methods: A descriptive case series study was conducted on 30 patients who underwent surgical intervention at the Department of Orthopedics and Traumatology, Can Tho Central General Hospital. Results: Male patients predominated, accounting for 26 of 30 cases, with a mean age of 36.8 years ± 2.65 (range: 8–65 years). The most common mechanism of injury was laceration by broken glass (66.7%). All patients sustained concomitant tendon injuries; vascular bundle injuries were identified in 50% of cases, and associated ulnar nerve injury was observed in 30%. All patients underwent microsurgical repair within 72 hours of injury. The mean follow-up duration was 8.5 months. Functional recovery was rated as good or above in 93.3% of cases. Conclusion: Median nerve transection at the forearm and wrist predominantly affects males of working age, most commonly caused by sharp object lacerations and frequently associated with tendon and vascular injuries. Early microsurgical intervention yields favorable functional outcomes, particularly in younger patients and those with fewer concomitant injuries.Ngoc Anh Duy ThachDang Ninh PhamMinh Tu Hoang
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510314915410.58490/ctjump.2026i103.4973CLINICAL, IMAGING CHARACTERISTICS AND SURGICAL OUTCOMES OF WHO GRADE II AND III MENINGIOMAS AT CAN THO CENTRAL GENERAL HOSPITAL IN 2024–2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4999
Background: WHO grade II and III meningiomas are central nervous system neoplasms characterized by rapid progression, invasiveness, and high recurrence rates. Radical surgical resection is pivotal for disease control. Objectives: To describe clinical, imaging characteristics, and surgical outcomes of WHO grade II and III meningiomas at Can Tho Central General Hospital (2024–2026). Materials and Methods: A prospective longitudinal study was conducted on 30 consecutive patients postoperatively diagnosed with WHO grade II and III meningiomas via histopathology (WHO 2016) at Can Tho Central General Hospital between 2024 and 2026. Results: The mean patient age was 58.2 ± 11.8 years, with 53.3% aged > 60 years and a female predominance of 73.3%. The most frequent presenting symptoms upon admission were headache (70.0%) and seizures (26.7%), while 23.3% were incidentally detected. On neuroimaging, 86.7% of tumors were located at the cranial convexity, 53.3% exhibited heterogeneous contrast enhancement, 56.7% had irregular margins, 90.0% demonstrated extensive peritumoral brain edema, 83.3% had dural tail sign, and 26.7% had bone invasion. The extent of surgical resection achieved Simpson grade I in 56.7% and Simpson grade II in 43.3% of cases. At the 3-month postoperative followup, 100.0% of patients were alive with no tumor progression or residue detected on follow-up magnetic resonace imaging, and 73.3% achieved favorable neurological recovery (KPS ≥ 80). A convexity tumor location was significantly associated with achieving Simpson I total resection (p = 0.024). Conclusion: Maximal microsurgical resection is an effective treatment modality for WHO grade II and III meningiomas, facilitating favorable functional recovery. A cranial convexity location serves as a statistically significant favorable factor for achieving Simpson grade I complete resection.Minh Tho NguyenViet My PhamDuy Linh NguyenThoai Ky HaThien Khiem TranDuc Tri Nguyen
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510315516210.58490/ctjump.2026i103.4999CLINICAL, PARACLINICAL FEATURES AND OUTCOMES OF RADICAL SURGERY FOR STAGE I-IIIA PRIMARY OVARIAN CANCER AT CAN THO ONCOLOGY HOSPITAL
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5181
Background: Ovarian cancer is one of the most common gynecologic malignancies and is associated with high mortality. Radical surgery plays an important role in the treatment of ovarian cancer and in prolonging patient survival. Objectives: To describe the clinical and paraclinical characteristics and evaluate the outcomes of radical surgery for primary ovarian cancer at stages I– IIIA. Materials and Methods: A cross-sectional descriptive study combined with a non-controlled clinical intervention was conducted in 31 patients with primary ovarian cancer who underwent radical surgery at Can Tho Oncology Hospital from January 2025 to May 2026. Results: The mean age was 55.3 ± 12.4 years, with stage I disease accounting for the majority (54.8%). Lower abdominal pain was the most common presenting symptom (77.4%), and elevated CA-12.5 levels were observed in 83.9% of patients. Contrast-enhanced computed tomography (CT) of the abdomen and pelvis showed a mean tumor size of 14.3 ± 5.9 cm, with mixed solid-cystic tumors being the predominant morphology (67.7%). The concordance rate between intraoperative frozen-section examination and final postoperative histopathology was 87.1%. Epithelial ovarian tumors accounted for 83.9% of cases. The mean operative time was 110 ± 43 minutes. Operative time was longer in patients with stage II disease than in those with stage I disease and was not associated with tumor size. No intraoperative complications were recorded. Postoperative complications included abdominal surgical-site infection (3.2%) and vaginal cuff infection (3.2%); both responded to medical treatment. According to the Clavien–Dindo classification, surgical outcomes were rated as good in 93.5% of patients and fair in 6.5%, with no moderate or poor outcomes. Conclusion: Primary ovarian cancer at stages I–IIIA predominantly occurs in older women and commonly presents with lower abdominal pain, elevated CA-12.5 levels, and mixed tumor morphology on imaging. Radical surgery is safe and associated with favorable outcomes, a low complication rate, and no recorded intraoperative complications.Hoang Vinh LeHuynh Trang VoThao Luat Huynh
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510316316910.58490/ctjump.2026i103.5181CLINICAL AND NEUROIMAGING CHARACTERISTICS OF PATIENTS WITH ACUTE ISCHEMIC STROKE
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4794
Background: Acute ischemic stroke remains a leading cause of mortality and long-term disability worldwide. The relationship between clinical presentation and neuroimaging is crucial for severity stratification and prognosis. Objectives: To describe the clinical and neuroimaging characteristics of AIS patients and to analyze their association. Materials and methods: A crosssectional analytical study was conducted on 125 patients with AIS treated at Can Tho Central General Hospital. Results: The mean age was 65.7 ± 12.0 years, and females accounted for 51.2% of cases. Most patients (75.2%) were admitted within 24 hours of symptom onset. The most common clinical manifestations were hemiparesis (92.8%), central facial palsy (48.0%), and aphasia (40.8%). Moderate to severe stroke severity according to the National Institutes of Health Stroke Scale (NIHSS) was observed in 56.0% of patients. Significant associations were found between NIHSS severity and arterial occlusion site (p < 0.001) as well as infarct size (OR = 3.47; KTC 95%: 1.53 - 7.89; p = 0.002). Moderate to severe cases were predominantly associated with middle cerebral and internal carotid artery occlusion and lesions of ≥ 15 mm. Conclusion: The study has elucidated the clinical and neuroimaging characteristics of patients with acute ischemic stroke, thereby confirming the correlation between stroke severity assessed by the NIHSS, the site of arterial occlusion, and infarct size.Chi Hieu PhamNgoc Tu LyThanh Nhu Nguyen
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510317017610.58490/ctjump.2026i103.4794CLINICAL CHARACTERISTICS AND SOME ASSOCIATED FACTORS OF CELLULITIS AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4370
Background: Cellulitis is a common skin and soft tissue infection that may lead to serious complications if not diagnosed and treated promptly. Data on the clinical characteristics and selected associated factors of cellulitis in Can Tho remain limited. Objectives: To describe 9 clinical characteristics and identify associated factors of cellulitis at Can Tho Hospital of DermatoVenereology from 2024 to 2025. Materials and Methods: A cross-sectional descriptive study was conducted to evaluate 9 clinical characteristics in 32 patients diagnosed with cellulitis at Can Tho Hospital of Dermato-Venereology from December 2024 to December 2025. Results: Prominent clinical characteristics included mild fever of 37.5-38°C (56.3%), lower extremity lesions (68.8%), single lesion (93.8%), lesion size 2-5 cm (62.5%), purulent (68.8%), pain (100%), erythematous plaques (84.4%); time from symptom onset to admission <3 days (62.5%). Some associated factors: diabetes with lesion count (p=0.011) and temperature (p=0.047); comorbidities with temperature (p=0.037) and lesion count (p=0.044); swimming with lesion count (p=0.006) and lesion size (p=0.001). Conclusion: Cellulitis is common in the over-40 age group with typical clinical presentation in the lower extremities accompanied by mild fever, pus, and pain with erythematous plaque lesions. Diabetes, comorbidities, and swimming are associated with lesion count, size, and admission temperature.Hoang Viet NguyenThi Kim Mai PhamThi Cam Tien BuiLan Chi TranThanh Tam NguyenThi Kim Ngan Lac
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510317718310.58490/ctjump.2026i103.4370FACTORS AFFECTING THE OUTCOMES OF RETROGRADE INTRARENAL SURGERY FOR KIDNEY STONES AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5211
Background: Retrograde intrarenal surgery (RIRS) using a flexible ureteroscope and laser lithotripsy has become a primary treatment option for kidney stones due to its high efficacy and safety. However, surgical outcomes are influenced by various factors related to stone characteristics and pelvicalyceal anatomy. Objectives: To evaluate the treatment outcomes and investigate factors affecting the stone-free rate (SFR) in patients undergoing RIRS at Can Tho University of Medicine and Pharmacy Hospital. Materials and methods: A prospective, non-controlled clinical intervention study was conducted on 75 patients with kidney stones treated with RIRS from May 2025 to May 2026. Results: The mean age was 50.4 ± 10.7 years, with males accounting for 54.7%. The overall success rate at 3 months was 90.7% (complete stone-free rate 82.7%, clinically insignificant residual fragments 8.0%). Factors negatively correlating with the SFR included multiple stones (73.9% vs. 86.5%, p=0.020), an acute infundibulopelvic angle (50.0% vs. 87.7% for moderate angle, p<0.001), larger stone size (p<0.001), and high stone density (p<0.001). Multivariate regression identified stone size and Hounsfield Unit (HU) density as independent prognostic factors increasing the risk of residual stones (p<0.001). Conclusions: RIRS is a safe and highly effective procedure. Large stone size and high stone density are the main factors reducing the complete SFR, necessitating careful preoperative imaging assessment.Vo Tan Phat QuachHuynh Tuan TranQuang Trung LeVan Huynh Duong
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2026-09-252026-09-2510318419010.58490/ctjump.2026i103.5211SURVEY ON DEFICIENCY CONSTITUTION AND ASSOCIATED LIFESTYLE FACTORS AMONG POSTGRADUATE STUDENTS OF TRADITIONAL CHINESE MEDICINE AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4774
Background: Deficiency constitution is a relatively common form of physical imbalance, particularly among populations undergoing high intellectual pressure and maintaining irregular lifestyle habits. To establish a reliable database for evaluating this condition in a specific professional group, we conducted a survey among postgraduate medical students. Objectives: To survey the prevalence of deficiency constitution among postgraduate students and to evaluate the relationship between the prevalence of deficiency constitution and the lifestyle habits of postgraduate students. Materials and methods: A cross-sectional descriptive study was conducted on 144 postgraduate students majoring in Traditional Chinese Medicine. Data were collected via a self-administered questionnaire. Results: The prevalence of Deficiency constitution was 47.2%, predominantly at a mild level (39.5%). The highest mean symptom scores were observed in the Systemic group (15.8 ± 5.5 points), manifested as fatigue and shortness of breath, followed by the Spleen-Stomach group (14.9 ± 5.3 points), characterized by abdominal bloating and poor appetite. Logistic regression analysis indicated a trend of higher prevalence of deficiency constitution among those with unhealthy lifestyle habits (including irregular dietary habits, low physical activity, and staying up late); however, this difference did not reach statistical significance (p > 0.05). Conclusion: Deficiency constitution assessed by CCMQ reflects suboptimal health status among a proportion of postgraduate students. The findings suggest a potential trend of lifestyle impact on antipathogenic Qi; thus, enhancing it through lifestyle modifications represents a practical preventive strategy.Gia Bao LeThi Ngoan LeNhat Minh TrangMinh Duong NguyenDinh Dang GiaDuy Linh DoanQuang Vinh Lam
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2026-09-252026-09-2510319119710.58490/ctjump.2026i103.4774KNOWLEDGE, ATTITUDES, PRACTICES REGARDING DROWNING PREVENTION AND ASSOCIATED FACTORS AMONG MIDDLE SCHOOL STUDENTS IN BINH THUY DISTRICT, CAN THO CITY IN 2025
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5237
Background: Drowning is a leading cause of mortality among children and adolescents globally and in Vietnam. According to the WHO Global Report on Drowning Prevention 2024, at least 3 million people have died from drowning over the past decade, with an estimated annual total exceeding 300,000 deaths, 43% of which occur among children under 14 years old. Objectives: To determine the levels of knowledge, attitudes, and practices regarding drowning prevention among middle school students in Binh Thuy District, Can Tho City, and to identify associated factors. Materials and methods: A cross-sectional descriptive study was conducted on 280 students from grades 6 to 9 currently enrolled at Tra An Middle School and Long Hoa Middle School, Binh Thuy District, Can Tho City. Results: The study recorded high rates of adequate attitudes (93.2%) and practices (62.5%) among students, but a low rate of adequate knowledge (35.7%). Grade level, swimming proficiency, school-based swimming lessons, and local drowning prevention communication were significantly associated with students' knowledge and practice (𝑝 < 0.05). Conclusions: The current status of attitudes and practices regarding drowning prevention among middle school students in Binh Thuy District is high. However, the level of knowledge in this group remains relatively low. Schools should collaborate with local authorities to organize extracurricular programs to enhance drowning prevention knowledge for students.Long Phi PhamPhuong Thao QuachThai Hung NguyenHoai Linh NguyenHuyen Tran TranVan Doi NguyenLe Ngoc Giau Nguyen
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510319820410.58490/ctjump.2026i103.5237THE CURRENT SITUATION OF ANXIETY AND SOME RELATED FACTORS AMONG STUDENTS IN HIGH SCHOOLS, CAN THO CITY IN 2025
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5039
Background: Currently, anxiety is increasing significantly, especially among high school students – an age group facing important life turning points (university entrance exams, career choices). Objectives: To describe the current state of anxiety and some related factors among high school students in Can Tho City in 2025. Materials and methods: This cross-sectional descriptive study analyzed 2015 students at 9 high schools in Can Tho City. A survey questionnaire was used to determine the rate of anxiety and some related factors among students. Results: The overall anxiety rate among high school students in Can Tho City in 2025 was 40.5%. Factors such as academic pressure, future career aspirations, parental expectations, and family discord are associated with anxiety among high school students. Conclusion: High school students in Can Tho in 2025 have a relatively high rate of anxiety, this indicates that anxiety among high school students remains a matter of concern and is linked to academic and family factors. It is necessary to strengthen schoolbased psychological counseling, provide stress management education for students, and enhance the role of families in supporting mental health.Le Anh Hong NguyenPhuong Thao NgoMinh Huu Le
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510320521010.58490/ctjump.2026i103.5039COMPARISON OF OUTCOMES OF ENDODONTIC TREATMENT IN LOWER MOLAR TEETH WITH CHRONIC APICAL PERIODONTITIS USING BIOACTIVE GLASS AND AH26 SEALER
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5112
Background: Currently, chronic apical periodontitis is effectively managed through nonsurgical endodontic treatment, with continuously improving clinical outcomes and expanding applications. Bioactive Glass sealer has demonstrated several advantages over conventional obturation materials. However, in Vietnam, there have been no published studies investigating the use of Bioactive Glass in the endodontic management of chronic apical periodontitis. Objectives: To describe the clinical and radiographic characteristics and to compare the treatment outcomes of non-surgical endodontic therapy in mandibular molars with chronic apical periodontitis obturated with Bioactive Glass and AH26 at Can Tho University of Medicine and Pharmacy Hospital during the 2025–2026 period. Materials and methods:A descriptive, interventional clinical study was conducted on two groups comprising 30 patients with mandibular molars diagnosed with chronic apical periodontitis indicated for endodontic treatment. Results: After 3 months, the reduction in PAI score in Group I (93%) was significantly higher than in Group II (60%) . After 6 months, the reduction in PAI score in Group I (100%) remained higher than in Group II (66.7%), with statistical significance. Conclusion: The endodontic treatment of mandibular molars with chronic apical periodontitis using Bioactive Glass as a root canal obturation material resulted in significant clinical and radiographic healing outcomes.Khanh Van BuiVan Duong HuynhNhut Tan LamThi Kim Ngoc Tran
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510321121710.58490/ctjump.2026i103.5112CLINICAL CHARACTERISTICS OF PATIENTS WITH MODERATE-TO-SEVERE ACNE VULGARIS AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY IN 2025-2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5008
Background: Acne vulgaris is a common chronic dermatological condition that significantly affects cosmetic appearance and the psychological well-being of many individuals. Objectives: to describe the clinical characteristics of patients with moderate-to-severe acne vulgaris at Can Tho Hospital of Dermato-Venereology in 2025-2026. Materials and method: A crosssectional descriptive study was conducted on 124 patients with moderate-to-severe acne vulgaris from August 2025 to February 2026. Results: The mean age of participants was 22.85 ± 3.81 years, with the 18 to 25 age group accounting for the highest proportion (72.6%). Females predominated over males, with a male-to-female ratio of 1/1.5. Pruritus or stinging sensations were reported by 37.1% of patients, while 24.2% experienced pain. All patients had facial acne lesions (100%), while the chest and back were also frequently involved, with prevalence rates of 37% and 43.5%, respectively. Inflammatory acne lesions such as papules, pustules, nodules, and cysts were highly prevalent, accounting for 98.4%, 87.1%, and 93.5%, respectively. Moderate acne had a higher proportion (62.9%), while severe acne accounted for 37.1%. The mean severity score according to the Global Acne Grading System was 27.21 ± 6.62. Among risk factors for moderate-to-severe acne, late sleeping and sleep deprivation were the most common, accounting for 80.6%. Conclusions: Moderate-to-severe acne vulgaris commonly affects young individuals. Patients may experience pruritus, stinging sensations, and pain. Acne lesions mainly involve the face and are characterized predominantly by inflammatory papules, pustules, and nodulocystic lesions, mainly at a moderate severity level. Family history of acne, high sugar intake, high dairy consumption, late bedtime, insufficient sleep and overweight were all significantly associated with severe acne.Van Linh BuiHuynh Trang Vo
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510321822410.58490/ctjump.2026i103.5008CLINICAL CHARACTERISTICS AND ASSOCIATED FACTORS OF CHEST AND BACK ACNE VULGARIS
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4369
Background: Acne vulgaris affecting the chest, back, and face is recognized to share a common pathogenesis, despite variations in localized cutaneous manifestations. Primarily prevalent among adults, this condition is modulated by a multifactorial interplay of age, gender, and genetic predisposition. Notably, the inflammatory process carries a significant risk of extensive scarring across broad anatomical regions. Such sequelae often result in substantial aesthetic impairment, necessitating comprehensive clinical management to mitigate long-term dermatological and psychological impacts. Objectives: To describe the clinical characteristics and assess various factors associated with chest and back acne vulgaris. Materials and Methods: A cross-sectional descriptive study on 55 patients with chest and back acne at Can Tho Hospital of DermatoVenereology from December 2024 to December 2025. Results: The majority of patients in the study were male (54.5%), aged 18 - 25 accounted for the highest proportion (45.5%). The position with the highest proportion is the back (65.5%). Common symptoms are itching (65.5%) and stinging (47.3%). Comedones (67.3%), papules (65.5%) are the most common. Acne severity is related to gender and cosmetic use with statistical significance. Conclusion: The majority of subjects in this study were male, predominantly within the 18–25 age demographic. Anatomically, the dorsal region (back) emerged as the most prevalent site of involvement. Patients frequently reported subjective symptoms of pruritus (itching) and stinging sensations. Morphologically, the cutaneous lesions consisted primarily of comedones and inflammatory papules. Notably, among patients presenting with moderate truncal acne, the male-to-female ratio was significantly skewed at 4:1. Furthermore, a positive correlation was observed between disease severity and topical product usage; subjects diagnosed with moderate-to-severe acne exhibited a substantially higher frequency of cosmetic application compared to those categorized as "almost clear" or possessing only mild involvement.Thi Nhu Huynh NguyenThoai Vi NguyenNguyen Anh Thu CaoDieu Bao HuynhDiem My VoThi Kim Ngan Lac
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2026-09-252026-09-2510322523010.58490/ctjump.2026i103.4369STUDY ON CLINICAL CHARACTERISTICS, ANXIETY LEVELS, AND TREATMENT OUTCOMES IN HERPES ZOSTER PATIENTS MANAGED WITH COMBINED HE-NE LASER THERAPY AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY IN 2025
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4396
Background: Herpes zoster is a dermatological condition characterized by the appearance of vesicular lesions along areas of skin innervated by sensory nerves, accompanied by pain. Many studies show that psychological factors can play a significant role in the progression and treatment outcome of the disease. The combination of He-Ne laser therapy, a topical treatment method combined with a treatment regimen, helps accelerate wound healing and reduce pain for patients. Objectives: To describe the clinical characteristics, anxiety levels, and evaluate the treatment outcomes of patients treated with He-Ne laser therapy for shingles. Materials and methods: A crosssectional descriptive study was conducted on 51 shingles patients at Can Tho Hospital of DermatoVenereology from May 2025 to October 2025. Results: The age group ≥ 60 accounted for 56.86%. The proportion of shingles patients was female (52.94%), higher than that of males (47.06%). The most common basic lesions were vesicles and bullae (96.08%), and erythema (90.2%). Anxiety was more prevalent in women than in men at all levels. Mild anxiety was most common in both sexes (29.41% in women; 23.53% in men). The majority of patients responded well to treatment (56.86%), with no anxiety after treatment (56.86%). The rate of mild anxiety also decreased to 37.25%, and only 5.89% of patients still experienced moderate anxiety. Conclusion: The age group ≥ 60 years predominated, reflecting the association between age and the risk of varicella zoster virus reactivation. The rate of anxiety in shingles patients was quite high, with mild anxiety accounting for 52.94% and only 33.33% having no anxiety. He-Ne laser therapy helps reduce pain, shorten healing time, improve mental well-being, and enhance overall treatment effectiveness for shingles patients.Hoang Khiem NguyenVan Ba HuynhTin Nghia TranHong Khoa Trang
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510323123710.58490/ctjump.2026i103.4396ESTABLISHMENT OF A LIPOPOLYSACCHARIDE (LPS)-INDUCED MEMORY IMPAIRMENT MODEL IN MICE
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5056
Background: The Lipopolysaccharide (LPS) model is a widely used experimental model for inducing memory impairment in animals. It offers several advantages, including high translational relevance, ease of establishment, robust and reproducible responses, and suitability for mechanistic investigations. However, to date, there have been relatively few domestic studies employing LPSinduced models of memory impairment. Objectives: To establishment LPS-induced memory impairment model in mice. Materials and methods: Memory impairment was induced in Swiss albino mice via intraperitoneal administration of lipopolysaccharide (LPS) at three dosage levels: 3 mg/kg, 5 mg/kg, and 7 mg/kg body weight. Outcomes were evaluated based on behavioral test of memory function and mortality rates. Results: LPS at doses of 5 mg/kg and 7 mg/kg induced comparable levels of memory impairment, both of which were more pronounced than those observed at the 3 mg/kg dose. Conclusions: This LPS-induced model of memory impairment was successfully established, with 5 mg/kg identified as the optimal dose.Thi Kim Ngan PhamThi Thu Huong PhanYen Linh CaoThanh Toan PhamHoang Anh Thu LeTran Bao Ngoc LeXuan Chu Duong
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510323824510.58490/ctjump.2026i103.5056CLINICAL CHARACTERISTICS AND PREVALENCE OF SELECTED POTENTIALLY ASSOCIATED FACTORS AMONG PATIENTS WITH NON-CARIOUS CERVICAL LESIONS IN PREMOLARS AT BINH CHANH HOSPITAL
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4795
Background: Early identification of the clinical characteristics, lesion severity, and potentially associated factors of non-carious cervical lesions (NCCLs) in premolars is important for guiding prevention, treatment, and long-term follow-up. Objectives: To describe the clinical characteristics and determine the proportions of selected potentially associated factors among patients with premolar NCCLs. Materials and Methods: A descriptive cross-sectional study was conducted among 50 patients with premolar NCCLs at Binh Chanh Hospital from July 2025 to March 2026. Results: Most patients were aged ≥ 40 years (66.0%), and 54.0% were male. Stimulusinduced dentin hypersensitivity was the most common reason for seeking care (86.0%). Lesions were more frequently located in the mandibular arch (58.0%), with a similar distribution between the right and left sides, and were predominantly found on the buccal surface (96.0%). Most lesions had a depth of 1-2 mm (74.0%). Wedge-shaped lesions were the predominant morphology (64.0%), and the most common location relative to the gingival margin was at the gingival margin level (60.0%). No tooth mobility was observed. Regarding toothbrushing practices, most patients brushed once or twice daily (58.0%), used soft-bristled toothbrushes (66.0%), and reported a vertical brushing technique (54.0%). Among the potentially associated factors assessed, consumption of acidic foods or carbonated beverages (34.0%) and acid regurgitation/gastroesophageal reflux (32.0%) were the most frequently reported. Conclusion: Premolar non-carious cervical lesions were commonly observed in patients aged ≥40 years, often presenting with dentin hypersensitivity and predominantly as wedge-shaped lesions on the buccal surface with a depth of 1-2 mm. Frequently observed potentially associated factors included acidic food and carbonated beverage consumption, gastroesophageal reflux, and toothbrushing characteristics.Thi Ai Van LeNguyen Lam LeHa Phuong Thao Tran
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510324625210.58490/ctjump.2026i103.4795RESEARCH ON THE PREVALENCE AND SOME FACTORS RELATED TO ANEMIA IN PATIENTS WITH TYPE 2 DIABETES AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN 2024-2025
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4451
Background: Type 2 diabetes mellitus is a common chronic disease with rapidly increasing prevalence globally. Anemia is a frequent complication in these patients but is often overlooked, directly affecting quality of life and prognosis. Objectives: To determine the prevalence and characteristics of anemia in patients with type 2 diabetes mellitus at Can Tho University of Medicine and Pharmacy Hospital in 2024-2025; To explore some factors associated with anemia in patients with type 2 diabetes mellitus at Can Tho University of Medicine and Pharmacy Hospital in 20242025. Materials and methods: A cross-sectional descriptive study was conducted on 191 patients with type 2 diabetes mellitus. Demographic and laboratory data were collected from medical records. Anemia was diagnosed when Hb < 13 g/dL (male) and < 12 g/dL (female). Data were analyzed using SPSS software with Chi-square and Mann-Whitney tests. Results: The overall prevalence of anemia was 27.7% (53/191). Most cases were mild (75.5%), with normocytic and normochromic red blood cells. Anemia was associated with gender (p=0.006) and chronic kidney disease stage (p=0.001) in the univariate analysis. Multivariate analysis identified male gender as an independent factor associated with anemia (p<0.001). Patients with impaired renal function (stages 3a–5) had a 2.27-fold higher risk of anemia compared with those in stages 1–2. Liver enzyme levels were significantly lower in the anemic group than in the non-anemic group. No significant associations were found with age group or glycemic control. Conclusion: The prevalence of anemia in type 2 diabetes mellitus patients is considerably high. Impaired renal function and male gender are critical associated factors requiring attention in clinical practice.Khanh Duy LamVan Hoang Kha NguyenThanh Phong DiepMinh Khoa NguyenThi Thu Thao TranCong Tru Le
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510325325910.58490/ctjump.2026i103.4451EVALUATING THE PREDICTIVE VALUE OF THE RESPIRATORY INDEX OF SEVERITY IN CHILDREN (RISC) SCORE FOR PNEUMONIA SEVERITY
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4864
Background: Pneumonia is the leading cause of mortality in children under 5 years of age. However, current severity assessment scoring systems are primarily designed for adults. The Respiratory Index of Severity in Children (RISC) is a specialized tool, but data on its application in Vietnam remains limited. This study aims to evaluate the predictive value of the RISC score for disease severity in pediatric pneumonia patients aged 2 months to 5 years. Objectives: To evaluate the predictive value of the RISC scale in determining the severity of community-acquired pneumonia in children aged 2 months to 5 years at a tertiary pediatric hospital in the Mekong Delta region. Materials and methods: A cross-sectional descriptive study with analysis was conducted on 120 children diagnosed with pneumonia and severe pneumonia, who were treated at Can Tho Children's Hospital from November 2024 to November 2025. Results: Male patients accounted for 55.8%, and the 12-60 month age group made up 56.7%. The proportion of severe pneumonia was 11%. A 1point increase in the RISC score was associated with a nearly 2-fold increased risk of progression to severe pneumonia (OR = 1.96; p = 0.003). The RISC score has predictive value for severe pneumonia with an area under the curve (AUC) of 0.746; at the cut-off value of 1 point, the sensitivity and specificity were 84.6% and 64.5%, respectively. Conclusion: The RISC score has good value in predicting the severity of pneumonia in children.Man Dat LePhuoc Sang NguyenViet Hung PhanNgoc Man PhamNguyen Nhat Phi HuynhThuy An NguyenPhi Khanh Nguyen
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510326026610.58490/ctjump.2026i103.4864PREVALENCE OF SERUM BICARBONATE REDUCTION AND RELATED FACTORS IN PATIENTS WITH CHRONIC KIDNEY DISEASE STAGES 4 AND 5
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4983
Background: Decreased serum bicarbonate is a common condition in patients with endstage chronic kidney disease, which accelerates disease progression and increases the risk of other complications. Determining the prevalence of decreased bicarbonate concentration and its associated factors helps clinicians develop timely intervention strategies. Objectives: To determine the prevalence of decreased serum bicarbonate concentration and investigate associated factors in patients with stage 4 and 5 chronic kidney disease. Materials and methods: An analytical crosssectional study was conducted on 53 outpatients with stage 4 and 5 chronic kidney disease at Can Tho Central General Hospital from October 2025 to May 2026. Decreased serum bicarbonate was defined as an HCO3- concentration <22mmol/L. Results: The prevalence of patients with decreased serum bicarbonate was 54.7%. Through multivariable regression analysis, independent factors increasing the risk of decreased bicarbonate included: stage 5 chronic kidney disease (OR=3.167; p=0.042), urea (OR=1.076; p=0.029), creatinine (OR=1.003; p=0.012), and serum chloride (OR=1.189; p=0.048). Conversely, an increase in hemoglobin concentration was an independent factor reducing this risk (OR=0.636; p=0.009). Conclusions: The prevalence of decreased bicarbonate in patients with stage 4 and 5 chronic kidney disease is 54.7%. Stage 5 chronic kidney disease, elevated urea, creatinine, and serum chloride, along with decreased hemoglobin, are factors associated with decreased bicarbonate concentration.Dong Khanh LeNhu Nghia NguyenThai Thanh Tam Tran
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510326727310.58490/ctjump.2026i103.4983THE CURRENT STATUS OF SLEEP QUALITY AND ASSOCIATED FACTORS AMONG THE ELDERLY IN MY KHANH COMMUNE, PHONG DIEN DISTRICT, CAN THO CITY IN 2025
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4822
Background: Sleep plays an essential role in restoring energy, strengthening the immune system, repairing cellular damage, and regulating hormones. Older adults often experience poor sleep quality such as insomnia, difficulty falling asleep, non-restorative sleep, or frequent nighttime awakenings. Objectives: To describe the current status of sleep quality and identify factors associated with sleep quality among the elderly in My Khanh Commune, Phong Dien District, Can Tho City in 2025. Materials and methods: A cross-sectional study was conducted on 197 elderly individuals aged 60 years and above in My Khanh Commune,Phong Dien District, Can Tho City in 2025. Assessment of sleep quality using the PSQI scale (good: ≤ 5 points, poor: >5 points). Results: The proportion of older adults with poor sleep quality was 53.81%. Poor sleep quality was significantly associated with personal income source, electronic device use, use of stimulants, use of analgesics, and nocturia frequency. Conclusion: The prevalence of poor sleep quality among older adults was relatively high. Therefore, appropriate intervention measures are needed to improve sleep quality and enhance the overall health of older adults.Thi Hong Tuyen NguyenTrong Nghia PhamNhat Duy TranThi Kim Thao NguyenHoang Phuong Thy NguyenHuynh Thien Nhan LyThi Kieu Lan NguyễnLam Phuong NgoThien Bao Lu
Copyright (c) 2026 Cantho Journal of Medicine and Pharmacy
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2026-09-252026-09-2510327428010.58490/ctjump.2026i103.4822CLINICAL AND PARACLINICAL CHARACTERISTICS, ASSOCIATED FEATURES, AND TREATMENT OUTCOMES OF ECTOPIC PREGNANCY WITH ≥300 mL OF HEMOPERITONEUM RECORDED AT SURGERY IN CAN THO FROM 2024 TO MARCH 2026
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/5099
Background: Ectopic pregnancy may cause hemoperitoneum and hemorrhagic shock. Describing surgically managed patients with a substantial volume of intraperitoneal blood may clarify their clinical manifestations and treatment outcomes. Objectives: To describe clinical and paraclinical characteristics and treatment outcomes, and to examine features associated with an intraoperative hemoperitoneum volume ≥300 mL among surgically managed ectopic pregnancies in Can Tho from 2024 to March 2026. Materials and methods: This retrospective cross-sectional study included 151 surgically managed ectopic pregnancies at two hospitals. The study outcome was operationally defined as ≥300 mL of intraperitoneal blood recorded at surgery. Results: Of 151 surgical cases, 64 (42.38%) had ≥300 mL of intraperitoneal blood. In this group, abdominal pain occurred in 95.31%, amenorrhea in 85.94%, vaginal bleeding in 67.19%, and moderate-to-large free intraperitoneal fluid on ultrasonography in 71.88%. An intraoperative hemoperitoneum volume of 500-1,000 mL was recorded in 57.81%; 46.88% received blood transfusion and 81.25% underwent laparoscopy. After adjustment, moderate-to-large intraperitoneal fluid on ultrasonography (aOR=10.39; 95% CI: 4.15-25.98; p<0.001) and posterior fornix tenderness (aOR=3.41; 95% CI: 1.28-9.11; p=0.014) remained associated with hemoperitoneum ≥300 mL. Conclusions: Among surgically managed ectopic pregnancies, 42.38% had ≥300 mL of intraperitoneal blood. Moderate-to-large free fluid and posterior fornix tenderness were concurrent manifestations of this outcome and should not be interpreted as causal risk factors, early-screening predictors, or evidence of delayed hospital presentation.Quoc Vi NguThi Hong Thai Phu
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2026-09-252026-09-2510328128710.58490/ctjump.2026i103.5099MEMORY FUNCTION CHARACTERISTICS AMONG INPATIENTS WITH SCHIZOPHRENIA AT HAI PHONG PSYCHIATRIC HOSPITAL IN 2024
https://tapchi.ctump.edu.vn/index.php/ctump/article/view/4737
Background: Memory dysfunction is a common cognitive deficit in schizophrenia and may affect patient care, health education, and rehabilitation. Objectives: To describe the characteristics of memory function in inpatients with schizophrenia at Hai Phong Mental Health Hospital in 2024. Materials and methods: A cross-sectional descriptive study was conducted among 95 inpatients with schizophrenia aged 20–64 years at Hai Phong Mental Health Hospital in 2024. Memory function was assessed using the Wechsler Memory Scale. Results were described according to the Memory Quotient (MQ) and clinically assessed memory domains. Data were analyzed using SPSS version 20.0. Results: The mean age of the participants was 45.3 ± 11.2 years, and 52.6% were male. The mean MQ score was 85.2 ± 14.1. A total of 69/95 patients (72.6%) had an MQ score below 90, corresponding to a score below the average range according to the classification used in this study. Among patients with MQ <90, short-term memory abnormalities were the most frequently observed (88.4%), followed by visuospatial memory abnormalities (79.7%), long-term memory abnormalities (75.4%), and immediate memory abnormalities (50.7%). Conclusion: Inpatients with schizophrenia showed relatively low overall memory scores, with short-term memory abnormalities most prominent. Memory assessment may be useful in psychiatric care and rehabilitation. Further controlled studies accounting for clinical symptoms and medication are needed to clarify the clinical significance of these findings.Van Lam NguyenThi Ngan VuPhuong Tien Duong Nguyen
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2026-09-252026-09-2510328829510.58490/ctjump.2026i103.4737